Target Name: VPS37C
NCBI ID: G55048
Other Name(s): hVps37C | vacuolar protein sorting 37C | VP37C_HUMAN | Vacuolar protein sorting 37C | PML39 | vacuolar protein sorting 37 homolog C | HVps37C | ESCRT-I complex subunit VPS37C | FLJ20847 | VPS37C, ESCRT-I subunit | Vacuolar protein sorting-associated protein 37C | VPS37C subunit of ESCRT-I

hVps37C: A Potential Drug Target for Cancer and Other Diseases

VPS37C, also known as hVps37C, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell division and has been identified as a potential drug target in the treatment of various diseases, including cancer.

The hVps37C protein is composed of 155 amino acid residues and has a calculated molecular weight of 19.1 kDa. It is expressed in a variety of tissues, including the brain, heart, liver, and muscle. It is involved in the regulation of cell division, cell adhesion, and the formation of tissues such as the nervous system and blood vessels.

One of the most promising aspects of hVps37C is its potential as a drug target. Studies have shown that hVps37C can be targeted by small molecules and antibodies, which could make it an attractive target for drug development. Additionally, hVps37C has been shown to be involved in the regulation of cellular processes that are associated with the development and progression of various diseases, including cancer.

One of the mechanisms by which hVps37C is thought to contribute to disease development is its role in the regulation of cell division. In cancer, abnormal cell division is a common feature, and hVps37C has been shown to be involved in the regulation of cell division in various tissues. For example, studies have shown that hVps37C is involved in the regulation of cell division in breast tissue and that it can inhibit the growth of cancer cells.

Another potential mechanism by which hVps37C contributes to disease development is its role in the regulation of cell adhesion. Adhesion is the process by which cells stick together and form tissues, and it is a critical aspect of the development and maintenance of tissues. hVps37C is involved in the regulation of cell adhesion in various tissues, and studies have shown that it can affect the strength and stability of cell-cell adhesion.

In addition to its role in cell division and cell adhesion, hVps37C is also involved in the regulation of the formation of tissues. It is a key regulator of the formation of the nervous system, and studies have shown that it plays a role in the development and maintenance of neural stem cells. Additionally, hVps37C is involved in the regulation of the formation of blood vessels, and studies have shown that it plays a role in the development and maintenance of blood vessels in various tissues.

Overall, hVps37C is a protein that is involved in a variety of cellular processes that are critical for the development and maintenance of tissues. Its potential as a drug target makes it an attractive target for the development of new treatments for a variety of diseases. Further research is needed to fully understand the role of hVps37C in disease development and to develop effective treatments.

Protein Name: VPS37C Subunit Of ESCRT-I

Functions: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation

More Common Targets

VPS37D | VPS39 | VPS41 | VPS45 | VPS4A | VPS4B | VPS50 | VPS51 | VPS51P8 | VPS52 | VPS53 | VPS54 | VPS72 | VPS8 | VPS9D1 | VPS9D1-AS1 | VRK1 | VRK2 | VRK3 | VRTN | VSIG1 | VSIG10 | VSIG10L | VSIG10L2 | VSIG2 | VSIG4 | VSIG8 | VSIR | VSNL1 | VSTM1 | VSTM2A | VSTM2A-OT1 | VSTM2B | VSTM2B-DT | VSTM2L | VSTM4 | VSTM5 | VSX1 | VSX2 | VTA1 | VTCN1 | VTI1A | VTI1B | VTN | VTRNA1-1 | VTRNA1-2 | VTRNA1-3 | VTRNA2-1 | VTRNA3-1P | VWA1 | VWA2 | VWA3A | VWA3B | VWA5A | VWA5B1 | VWA5B2 | VWA7 | VWA8 | VWC2 | VWC2L | VWCE | VWDE | VWF | VXN | WAC | WAC-AS1 | WAKMAR1 | WAKMAR2 | WAPL | WARS1 | WARS2 | WARS2-AS1 | WAS | WASF1 | WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2