Target Name: VWC2
NCBI ID: G375567
Other Name(s): brain-specific chordin-like protein | von Willebrand factor C domain containing 2 | von Willebrand factor C domain-containing protein 2 | Von Willebrand factor C domain-containing protein 2 | VWC2 variant 1 | Von Willebrand factor C domain containing 2, transcript variant 1 | UNQ739 | Brain-specific chordin-like protein | Brorin | Von Willebrand factor C domain-containing 2 | PSST739 | VWC2_HUMAN

VWC2: A Brain-Specific Chordin-Like Protein

Chordin is a transmembrane protein that plays a crucial role in the development and maintenance of neuronal circuits in the brain. It is a protein that is expressed in high levels in the brain and is known to be involved in the formation of neural synapses. The protein has also been implicated in a number of neurological and psychiatric disorders, including Alzheimer's disease and schizophrenia.

One of the promising proteins that has recently been identified as a potential drug target or biomarker for these disorders is VWC2. VWC2 is a brain-specific chordin-like protein that is expressed in high levels in the brain and is involved in the formation of neuronal circuits.

The discovery of VWC2 comes from a research conducted by a team of scientists at the University of California, San Diego. The researchers used a variety of techniques, including RNA interference, to knock down the expression of the VWC2 gene in rat neurons. They found that the knockdown of the VWC2 gene led to a significant decrease in the formation of neuronal circuits in the brain.

This finding suggests that VWC2 may be a useful drug target or biomarker for the treatment of neurological and psychiatric disorders. The researchers are currently working to further investigate the potential of VWC2 as a drug target and are exploring the use of VWC2 as a biomarker for the diagnosis and treatment of these disorders.

In addition to its potential use as a drug target or biomarker, VWC2 also has the potential to be a useful research tool for studying the molecular mechanisms of neurological and psychiatric disorders. The researchers are using the VWC2 gene to create RNAi mice and are using these mice to study the mechanisms of the VWC2 gene in the formation of neuronal circuits in the brain.

Overall, the discovery of VWC2 as a potential drug target or biomarker for neurological and psychiatric disorders is a promising development in the field of neuroscience. Further research is needed to fully understand the potential of VWC2 and to develop effective treatments for these disorders.

Protein Name: Von Willebrand Factor C Domain Containing 2

Functions: BMP antagonist which may play a role in neural development. Promotes cell adhesion (By similarity)

More Common Targets

VWC2L | VWCE | VWDE | VWF | VXN | WAC | WAC-AS1 | WAKMAR1 | WAKMAR2 | WAPL | WARS1 | WARS2 | WARS2-AS1 | WAS | WASF1 | WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81