WDR7: Key Regulator of Cell Signaling Pathways and Potential Drug Target
WDR7: Key Regulator of Cell Signaling Pathways and Potential Drug Target
WDR7 (Western blot analysis Repeat Domain 7) is a protein that is expressed in various tissues and cells throughout the body. It is a repeat domain containing 7 transmembrane spans and is characterized by a unique secondary structure that is composed of a central transmembrane domain and two long extracellular loops (Figure 1).
WDR7 is a key regulator of cell signaling pathways, and it is involved in the development and maintenance of various tissues and organs (Figure 2). For example, WDR7 has been shown to be involved in the regulation of cell adhesion, migration and invasion ( image 3).
WDR7 has also been shown to play a role in the regulation of cell survival and metabolism. For example, studies have shown that WDR7 can promote the survival of cancer cells and that it is involved in the regulation of cell proliferation (Figure 4).
In addition to its role in cell signaling pathways, WDR7 is also a potential drug target. The WDR7 gene has been shown to be highly expressed in various tissues and cells, including cancer cells (Figure 5). Additionally, studies have shown that WDR7 can be targeted by small molecules, such as inhibitors, which can inhibit its function (Figure 6).
WDR7 is also a potential biomarker for various diseases, including cancer. The expression of WDR7 has been shown to be elevated in various types of cancer, including breast, lung, and ovarian cancer (Figure 7). Additionally, studies have shown that WDR7 can be used as a diagnostic marker for cancer, as its expression is often increased in cancer cells compared to normal cells (Figure 8).
In conclusion, WDR7 is a protein that is involved in various signaling pathways and has been shown to play a role in the regulation of cell adhesion, migration, and invasion. It is also a potential drug target and biomarker for various diseases, including cancer. Further research is needed to fully understand the role of WDR7 in these processes and to develop effective treatments for these diseases.
Protein Name: WD Repeat Domain 7
More Common Targets
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