WDR31: A Protein Involved in Cell Growth, Differentiation and Disease
WDR31: A Protein Involved in Cell Growth, Differentiation and Disease
WDR31 (WDR31_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including neurodegenerative disorders, cancer, and inflammation.
One of the key functions of WDR31 is its role in cell-cycle regulation. It is a component of the spindle, which is the structure that forms the mitotic spindle that pulls the chromosomes of the cell during cell division. WDR31 helps to maintain the integrity of the spindle by regulating the distribution of the microtubules that make up the spindle.
In addition to its role in cell-cycle regulation, WDR31 has also been shown to play a key role in the regulation of gene expression. It has been shown to interact with a variety of transcription factors, including T-cell factor (TGF-β ), which is a key regulator of cell growth and differentiation.
WDR31 has also been shown to be involved in the regulation of cellular immigration. It has been shown to play a key role in the migration of immune cells to the site of an infection, and is required for the development of cancer.
In addition to its role in cell-cycle regulation and cellular immigration, WDR31 has also been implicated in the regulation of a variety of other processes, including the regulation of cell survival, the response to chemotherapy, and the regulation of inflammation.
Given its involvement in so many important processes in the cell, it is not surprising that WDR31 has become a drug target for a number of diseases. For example, it has been shown to be involved in the development of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. It has also been shown to be involved in the development of cancer, including breast and ovarian cancer.
In addition to its potential as a drug target, WDR31 is also a potential biomarker for a number of diseases. For example, it has been shown to be elevated in the blood of people with Alzheimer's disease, and may be a useful diagnostic marker for this disease. It has also been shown to be elevated in the urine of people with breast cancer, and may be a useful biomarker for this disease.
Overall, WDR31 is a protein that has important roles in a variety of cellular processes, including cell-cycle regulation, gene expression, and cellular immigration. Its potential as a drug target and biomarker make it an attractive target for research into a variety of diseases . Further research is needed to fully understand the role of WDR31 in these processes and its potential as a therapeutic agent.
Protein Name: WD Repeat Domain 31
More Common Targets
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