Target Name: WDR44
NCBI ID: G54521
Other Name(s): WDR44 variant 1 | WD repeat-containing protein 44 | Rabphilin-11 | WD repeat domain 44 | SYM-4 | RAB11BP | WDR44_HUMAN | RPH11 | rabphilin-11 | WD repeat domain 44, transcript variant 1 | WD repeat-containing protein 44 (isoform 1)

WDR44: A Potential Drug Target and Biomarker

WDR44 is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer. The gene, which encodes a protein known as WDR44, is located on chromosome 6 and has been shown to play a role in the development and progression of various diseases.

One of the key features of WDR44 is its role in the regulation of cell growth and differentiation. The protein encoded by the WDR44 gene is known to be involved in the inhibition of the cell cycle, which is the process by which cells divide and grow. This is important for the development and progression of cancer, as the inhibition of cell division can lead to the formation of cancer cells.

Another key function of WDR44 is its role in the regulation of cell survival. The protein encoded by the WDR44 gene has been shown to be involved in the inhibition of cell apoptosis, which is the process by which cells die as a result of environmental or genetic stress. This is important for the development and progression of diseases, as the inhibition of cell apoptosis can lead to the continuation of cell growth and the formation of new disease.

In addition to its role in cell cycle and apoptosis, WDR44 has also been shown to be involved in the regulation of cell adhesion. The protein encoded by the WDR44 gene is known to be involved in the formation of tight junctions, which are a type of cell adhesion that helps to maintain the integrity of tissues. This is important for the development and progression of diseases, as the disruption of cell adhesion can lead to the formation of new tumors.

Furthermore, WDR44 is also known to be involved in the regulation of inflammation. The protein encoded by the WDR44 gene has been shown to be involved in the regulation of inflammation and the immune response. This is important for the development and progression of diseases, as the regulation of inflammation and the immune response can contribute to the development and progression of diseases.

In conclusion, WDR44 is a gene that has been identified as a potential drug target and biomarker for various diseases. Its role in the regulation of cell cycle, apoptosis, and adhesion, as well as its involvement in the regulation of inflammation, make it an attractive target for drug development. Further research is needed to fully understand the potential of WDR44 as a drug and to identify its potential therapeutic uses.

Protein Name: WD Repeat Domain 44

Functions: Downstream effector for RAB11. May be involved in vesicle recycling (By similarity)

More Common Targets

WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1 | WDR87 | WDR88 | WDR89 | WDR90 | WDR91 | WDR93 | WDR97 | WDSUB1 | WDTC1 | WEE1 | WEE2 | WEE2-AS1 | WFDC1 | WFDC10A | WFDC10B | WFDC11 | WFDC12 | WFDC13 | WFDC2 | WFDC21P | WFDC3 | WFDC5 | WFDC6 | WFDC8 | WFDC9 | WFIKKN1 | WFIKKN2 | WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1