WDFY4: A Potential Drug Target and Biomarker (G57705)
WDFY4: A Potential Drug Target and Biomarker
The protein WDFY4, also known as WDFY4-containing protein 4, is a protein that has been identified as a potential drug target and biomarker. WDFY4 is a 21-kDa protein that is expressed in various tissues, including muscle, heart, brain, and kidney. It is composed of two distinct domains: a N-terminal transmembrane domain and a C-terminal cytoplasmic domain.
The N-terminal transmembrane domain of WDFY4 contains a unique structural feature known as a variable region. This region is composed of a long amino acid sequence that is responsible for the protein's ability to enter the endoplasmic reticulum (ER) and for its subsequent cytoplasmic localization. The variable region of WDFY4 contains several unique amino acids that are specific to this protein and are involved in its function.
The C-terminal cytoplasmic domain of WDFY4 is responsible for the protein's ability to interact with other cellular structures and for its role in cellular signaling. This domain contains several unique amino acids that are specific to this protein and are involved in its function.
WDFY4 has been shown to play a role in several cellular processes, including the regulation of cellular signaling pathways, cell division, and protein synthesis. It has also been shown to interact with several different proteins, including the protein tyrosine kinase (TK) and the protein serine/thionine-protein kinase (STK).
Based on these findings, it is possible that WDFY4 could be a drug target. By inhibiting the activity of WDFY4, it may be possible to treat a variety of cellular processes that are affected by this protein, including the regulation of cellular signaling pathways, cell division, and protein synthesis. This could lead to the development of new treatments for a variety of diseases.
In addition to its potential as a drug target, WDFY4 has also been shown to be a potential biomarker. Its unique structure and the proteins with which it interacts suggest that it could be used as a diagnostic tool for a variety of diseases. For example, if WDFY4 is expressed abnormally in a particular tissue or at a particular level, it may be a diagnostic indicator of a variety of diseases, including neurodegenerative disorders, cancer, and cardiovascular disease.
In conclusion, WDFY4 is a protein that has the potential to be a drug target and biomarker. Its unique structure and the proteins with which it interacts suggest that it could be used to treat a variety of cellular processes and to serve as a diagnostic tool for a variety of diseases. Further research is needed to fully understand the function and potential of this protein.
Protein Name: WDFY Family Member 4
Functions: Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Also plays a role in B-cell survival through regulation of autophagy
More Common Targets
WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5 | WDR53 | WDR54 | WDR55 | WDR59 | WDR5B | WDR6 | WDR62 | WDR64 | WDR7 | WDR70 | WDR72 | WDR73 | WDR74 | WDR75 | WDR76 | WDR77 | WDR81 | WDR82 | WDR82P1 | WDR83 | WDR83OS | WDR86 | WDR86-AS1 | WDR87 | WDR88 | WDR89 | WDR90 | WDR91 | WDR93 | WDR97 | WDSUB1 | WDTC1 | WEE1 | WEE2 | WEE2-AS1 | WFDC1 | WFDC10A | WFDC10B | WFDC11 | WFDC12 | WFDC13 | WFDC2 | WFDC21P | WFDC3 | WFDC5 | WFDC6 | WFDC8 | WFDC9 | WFIKKN1 | WFIKKN2 | WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2
