Target Name: VTI1A
NCBI ID: G143187
Other Name(s): Vesicle transport through interaction with t-SNAREs homolog 1A | vesicle transport through interaction with t-SNAREs 1A | Vti1-rp2 | MMDS3 | VTI1A_HUMAN | Vesicle transport through interaction with t-SNAREs 1A, transcript variant 1 | Vesicle transport v-SNARE protein Vti1-like 2 | VTI1A variant 2 | Vesicle transport through interaction with t-SNAREs 1A, transcript variant 2 | vesicle transport v-SNARE protein Vti1-like 2 | MVti1 | Vesicle transport through interaction with t-SNAREs homolog 1A (isoform b) | VTI1A variant 1 | VTI1RP2 | SNARE Vti1a-beta protein | Vesicle transport through interaction with t-SNAREs homolog 1A (isoform a)

VTI1A: A Protein Regulating Endosomal System and Cellular Processes

VTI1A, also known as Vesicle Transport Through Interaction with T-SNAREs Homolog 1A, is a protein that plays a crucial role in the transport of vesicles from the endoplasmic reticulum (ER) to various intracellular organelles, including the endoplasmic reticulum itself. It belongs to the family of transmembrane protein (TMP) and is composed of a long cytoplasmic tail and a transmembrane domain.

VTI1A is a key protein for the transport of various types of vesicles, including solutes, ions, and organelles. It has been shown to play a critical role in the regulation of endosomal system (ES) and is involved in the delivery of vesicles to the cytosol, the endoplasmic reticulum, and the endoplasmic reticulum-to-endoplasmic reticulum (ER-ER) transport.

One of the unique features of VTI1A is its ability to interact with the protein t-SNAREs homolog 1A (T-SNARE), which is also a key protein for the delivery of vesicles to the ER. This interaction between VTI1A and T-SNAREs homolog 1A suggests that they may work together to regulate vesicle transport and may be potential drug targets or biomarkers.

The VTI1A-T-SNAREs homolog 1A interaction suggests that VTI1A may be a negative regulator of T-SNAREs homolog 1A, which would mean that it would prevent T-SNAREs homolog 1A from functioning and interacting with other proteins. This would suggest that VTI1A may play a role in T-SNAREs homolog 1A-mediated processes and could potentially be a drug target or biomarker for T-SNAREs homolog 1A-mediated diseases.

In addition to its potential role as a negative regulator of T-SNAREs homolog 1A, VTI1A has also been shown to interact with various other proteins, including the protein transmembrane protein (TMP) family. This suggests that VTI1A may be involved in the regulation of various cellular processes, including the regulation of endosomal system (ES) and the regulation of cytoskeletal organization.

VTI1A is also known to play a role in the regulation of various cellular processes, including the regulation of cell adhesion, cell migration, and the regulation of the cytoskeleton. It has been shown to interact with proteins involved in these processes, including the protein cadherin and the protein filament (F-actin).

In conclusion, VTI1A is a protein that has been shown to play a critical role in various cellular processes, including the regulation of endosomal system (ES), the regulation of cytoskeletal organization, and the regulation of cell adhesion and migration. Its interaction with T -SNAREs homolog 1A suggests that it may be a potential drug target or biomarker for T-SNAREs homolog 1A-mediated diseases. Further research is needed to fully understand the role of VTI1A in these processes and to determine its potential as a drug target or biomarker .

Protein Name: Vesicle Transport Through Interaction With T-SNAREs 1A

Functions: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence

More Common Targets

VTI1B | VTN | VTRNA1-1 | VTRNA1-2 | VTRNA1-3 | VTRNA2-1 | VTRNA3-1P | VWA1 | VWA2 | VWA3A | VWA3B | VWA5A | VWA5B1 | VWA5B2 | VWA7 | VWA8 | VWC2 | VWC2L | VWCE | VWDE | VWF | VXN | WAC | WAC-AS1 | WAKMAR1 | WAKMAR2 | WAPL | WARS1 | WARS2 | WARS2-AS1 | WAS | WASF1 | WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1 | WDR11 | WDR11-DT | WDR12 | WDR13 | WDR17 | WDR18 | WDR19 | WDR20 | WDR24 | WDR25 | WDR26 | WDR27 | WDR3 | WDR31 | WDR33 | WDR35 | WDR35-DT | WDR36 | WDR37 | WDR38 | WDR4 | WDR41 | WDR43 | WDR44 | WDR45 | WDR45B | WDR46 | WDR47 | WDR48 | WDR49 | WDR5