Target Name: VPS53
NCBI ID: G55275
Other Name(s): VPS53_HUMAN | MGC39512 | VPS53 subunit of GARP complex, transcript variant 1 | Vacuolar protein sorting-associated protein 53 homolog (isoform 1) | VPS53 variant 1 | Vacuolar protein sorting-associated protein 53 homolog | PCH2E | VPS53, GARP complex subunit | HCCS1 | FLJ10979 | VPS53 subunit of GARP complex | hepatocellular carcinoma suppressor 1 | hVps53L | pp13624

Exploring The Potential of VPS53 as A Drug Target

VPS53 (Valproic acid) is a drug target (also known as a biomarker) that has been identified by researchers using a variety of techniques, including high-throughput screening and gene expression analysis. In this article, we will explore the research on VPS53 and its potential as a drug target, as well as the potential implications of this research for the treatment of various diseases.

VPS53 is a gene that encodes a protein known as VPS53, which is a key regulator of microRNA (miRNA) levels in the body. miRNA are small non-coding RNAs that play a critical role in regulating gene expression, and are often altered in diseases such as cancer, neurodegenerative diseases, and mental disorders.

Research has shown that VPS53 is involved in the regulation of a wide range of genes, including those involved in cell growth, differentiation, and stress response. It has also been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and mental disorders.

One of the key reasons for the interest in VPS53 is its potential as a drug target. By targeting the regulation of VPS53, researchers may be able to develop new treatments for a variety of diseases. For example, VPS53 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, and may be a potential target for these conditions.

In addition to its potential as a drug target, VPS53 has also been shown to be involved in the regulation of various biological processes that are important for human health. For example, VPS53 has been shown to play a role in the regulation of cell stress response, which is important for the maintenance of cellular health and homeostasis.

Research has also shown that VPS53 is involved in the regulation of cellular processes that are important for the development and maintenance of tissues and organs. For example, VPS53 has been shown to play a role in the regulation of stem cell proliferation and the development of tissues and organs, which is important for the development and maintenance of tissues and organs.

In conclusion, VPS53 is a gene that has been shown to be involved in a wide range of biological processes that are important for human health. As a drug target, VPS53 has the potential to be used to develop new treatments for a variety of diseases, including cancer, neurodegenerative diseases, and mental disorders. Further research is needed to fully understand the role of VPS53 in these processes and to develop effective treatments.

Protein Name: VPS53 Subunit Of GARP Complex

Functions: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061)

More Common Targets

VPS54 | VPS72 | VPS8 | VPS9D1 | VPS9D1-AS1 | VRK1 | VRK2 | VRK3 | VRTN | VSIG1 | VSIG10 | VSIG10L | VSIG10L2 | VSIG2 | VSIG4 | VSIG8 | VSIR | VSNL1 | VSTM1 | VSTM2A | VSTM2A-OT1 | VSTM2B | VSTM2B-DT | VSTM2L | VSTM4 | VSTM5 | VSX1 | VSX2 | VTA1 | VTCN1 | VTI1A | VTI1B | VTN | VTRNA1-1 | VTRNA1-2 | VTRNA1-3 | VTRNA2-1 | VTRNA3-1P | VWA1 | VWA2 | VWA3A | VWA3B | VWA5A | VWA5B1 | VWA5B2 | VWA7 | VWA8 | VWC2 | VWC2L | VWCE | VWDE | VWF | VXN | WAC | WAC-AS1 | WAKMAR1 | WAKMAR2 | WAPL | WARS1 | WARS2 | WARS2-AS1 | WAS | WASF1 | WASF2 | WASF3 | WASF4P | WASF5P | WASH complex | WASH2P | WASH3P | WASH4P | WASH5P | WASH6P | WASH7P | WASH8P | WASHC1 | WASHC2A | WASHC2C | WASHC3 | WASHC4 | WASHC5 | WASIR1 | WASL | WAVE1 complex | WBP1 | WBP11 | WBP11P1 | WBP1L | WBP2 | WBP2NL | WBP4 | WDCP | WDFY1 | WDFY2 | WDFY3 | WDFY3-AS2 | WDFY4 | WDHD1 | WDPCP | WDR1