Target Name: OR2T33
NCBI ID: G391195
Other Name(s): olfactory receptor family 2 subfamily T member 33 | O2T33_HUMAN | OR1-56 | OR2T32 | Olfactory receptor 2T33 | Novel 7 transmembrane receptor (rhodopsin family) protein | Olfactory receptor OR1-56 | olfactory receptor OR1-56 | novel 7 transmembrane receptor (rhodopsin family) protein | Olfactory receptor family 2 subfamily T member 33

OR2T33: A Potential Drug Target and Biomarker for Olfactory Receptor Function

Olfactory receptors (ORs) are a family of transmembrane G protein-coupled receptors (GPCRs) that play a crucial role in mediating sensory experiences, including taste and smell. The OR2T33 gene, located within the Olfactory Receptor Family 2 (ORF2) subfamily T member 33, is a known gene encoding a GPCR that is expressed in the olfactory system. This gene has been the focus of intense research in recent years due to its potential as a drug target or biomarker.

The OR2T33 gene encodes a 154 amino acid long protein that contains a unique farnesylated cysteine 鈥嬧?媟esidue at its C-terminus. This cysteine 鈥嬧?媟esidue is known as a conserved modification, which is characterized by the addition of a sulfur atom to the cysteine 鈥嬧?媠ide chain. This modification has been shown to play a critical role in the stability and function of ORs, as well as in the regulation of cellular processes such as cell growth, differentiation, and apoptosis.

OR2T33 has been shown to be involved in the regulation of olfactory receptor function. ORs are involved in the perception of various sensory stimuli, including food, fragrances, and environmental stimuli. The OR2T33 gene has been shown to be involved in the regulation of the expression and function of ORs, which suggests that it may play a critical role in the sense of smell.

In addition to its involvement in olfactory receptor function, OR2T33 has also been shown to be involved in the regulation of other cellular processes. For example, OR2T33 has been shown to be involved in the regulation of cell adhesion, a process that is critical for the maintenance of tissue structure and function. OR2T33 has also been shown to be involved in the regulation of cell signaling pathways, including the TGF-β pathway, which is involved in the regulation of cell growth, differentiation, and survival.

Due to its involvement in the regulation of olfactory receptor function and other cellular processes, OR2T33 has been identified as a potential drug target or biomarker. Researchers have shown that inhibiting the activity of OR2T33 using small interfering RNA (siRNA) or genetic modifiers can modulate the function of ORs, including the sensitivity to sensory stimuli and the regulation of cellular processes. This suggests that OR2T33 may be a useful target for the development of new treatments for sensory disorders, such as taste and smell loss, as well as for other cellular processes that are involved in the regulation of olfactory receptor function.

In conclusion, OR2T33 is a gene that has been shown to be involved in the regulation of olfactory receptor function and other cellular processes. Its unique farnesylated cysteine 鈥嬧?媘odification and its involvement in the regulation of olfactory receptor function make it a potential drug target or biomarker for the development of new treatments for sensory disorders. Further research is needed to fully understand the role of OR2T33 in the regulation of olfactory receptor function and its potential as a drug target or biomarker.

Protein Name: Olfactory Receptor Family 2 Subfamily T Member 33

Functions: Odorant receptor

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OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9 | OR4E2 | OR4F13P | OR4F15 | OR4F16 | OR4F17 | OR4F21 | OR4F29 | OR4F3 | OR4F4 | OR4F5 | OR4F6 | OR4G3P | OR4K1 | OR4K13 | OR4K14 | OR4K15 | OR4K17 | OR4K2 | OR4K5 | OR4K6P | OR4K7P | OR4L1 | OR4M1 | OR4M2 | OR4M2-OT1 | OR4N2 | OR4N3P | OR4N4 | OR4N5 | OR4P4 | OR4Q3 | OR4S1 | OR4S2 | OR4T1P | OR4V1P | OR4X1 | OR4X2 | OR51A1P | OR51A2 | OR51A3P | OR51A4 | OR51A6P | OR51A7 | OR51B2 | OR51B4 | OR51B5 | OR51B6 | OR51C1P | OR51D1 | OR51E1 | OR51E2 | OR51F1