Target Name: USP17L7
NCBI ID: G392197
Other Name(s): Ubiquitin specific peptidase 17 like family member 7 | Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7 | U17L7_HUMAN | ubiquitin specific peptidase 17 like family member 7 | ubiquitin specific peptidase 17-like 7 | Ubiquitin specific peptidase 17-like 7

USP17L7: A Potential Drug Target and Biomarker for Ubiquitin Specific Peptidase 17-Like Family Member 7

Introduction

Ubiquitin specific peptidase 17-like family member 7 (USP17L7) is a protein that plays a crucial role in the regulation of protein degradation in the body. It is a member of the ubiquitin-proteasome system (UPS), which is responsible for removing damaged or unnecessary proteins from the cell. USP17L7 is involved in the degradation of a wide variety of proteins, including caseins, which are important for muscle growth and development.

Despite its importance, USP17L7 has been until now, overlooked as a potential drug target or biomarker. However, recent studies have identified potential targets for USP17L7, which may reveal its true potential as a drug. In this article, we will explore the biology and potential drug targets of USP17L7.

The biology of USP17L7

USP17L7 is a 23-kDa protein that is expressed in various tissues, including muscle, heart, and brain. It is a single-pass protein that belongs to the Ubiquitin specific peptidase 17-like family member 7. This family includes a variety of proteins that share a conserved catalytic core and a specific structural domain, known as the 尾-sheet.

USP17L7 is involved in the degradation of a wide variety of proteins, including caseins, which are important for muscle growth and development. It has also been shown to interact with caseins and to play a role in the regulation of protein degradation. to interact with the proteinBeclin-1 (Bec1), which is involved in cell signaling and is a known regulator of USP17L7.

Potential drug targets for USP17L7

Several studies have identified potential drug targets for USP17L7. One of the most promising targets is the protein known as Z-DNA, which is a component of the chromatin complex. USP17L7 has been shown to interact with Z-DNA and has been proposed as a potential drug target for the treatment of various diseases, including cancer.

Another potential drug target for USP17L7 is the protein known as p120G, which is a component of the endoplasmic reticulum (ER) and is involved in protein degradation. USP17L7 has been shown to interact with p120G and has been proposed as a potential drug target for the treatment of various diseases, including neurodegenerative disorders.

Biomarkers for USP17L7

USP17L7 has also been identified as a potential biomarker for several diseases. For example, USP17L7 has been shown to be involved in the regulation of muscle growth and development, and has been proposed as a potential biomarker for muscle-related diseases, such as dystopian muscle diseases and myopathies.

USP17L7 has also been shown to be involved in the regulation of protein degradation, which is a critical process for the maintenance of cellular homeostasis. This makes it a potential biomarker for diseases that are characterized by the accumulation of damaged or unnecessary proteins, such as neurodegenerative disorders.

Conclusion

In conclusion, USP17L7 is a protein that plays a crucial role in the regulation of protein degradation in the body. Its potential as a drug target or biomarker has been identified, and further studies are needed to fully understand its biology and clinical potential.

Protein Name: Ubiquitin Specific Peptidase 17 Like Family Member 7

More Common Targets

USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5 | USP50 | USP51 | USP53 | USP54 | USP6 | USP6NL | USP6NL intronic transcript 1 (non-protein coding), transcript variant 1 | USP7 | USP8 | USP8P1 | USP9X | USP9Y | USPL1 | UST | UTF1 | UTP11 | UTP14A | UTP14C | UTP15 | UTP18 | UTP20 | UTP23 | UTP25 | UTP3 | UTP4 | UTP6 | UTRN | UTS2 | UTS2B | UTS2R | UTY | UVRAG | UVSSA | UXS1 | UXT | UXT-AS1 | VAC14 | Vacuolar H+ ATPase | VAMP1 | VAMP2 | VAMP3 | VAMP4 | VAMP5 | VAMP7 | VAMP8 | VANGL1 | VANGL2 | VAPA | VAPB | VARS1 | VARS2 | Vascular endothelial growth factor receptor (VEGFR) | Vascular endothelial growth factors (VEGF) | VASH1 | VASH1-AS1