UTP23: A Potential Drug Target and Biomarker for Small Subunit Processes

Target Name: UTP23

NCBI ID: G84294

UTP23: A Potential Drug Target and Biomarker for Small Subunit Processes

Introduction

The processome is a complex protein-protein interaction network that plays a crucial role in cellular signaling and regulation. It is made up of multiple subunits that interact with one another to generate diverse signaling pathways. One of the key subunits involved in this network is UTP23 . UTP23 is a small subunit of the processome that is expressed in many different cell types and is involved in various cellular processes, including intracellular signaling, protein folding, and transport.

UTP23 has been identified as a potential drug target and biomarker due to its unique structure and function. It is a protein that is composed of a single polypeptide chain and has a unique farnesylated cysteine 鈥嬧?媟esidue at its N-terminus. This cysteine 鈥嬧?媟esidue is known to be a target for small molecule inhibitors, making UTP23 an attractive target for drug development.

In this article, we will discuss the biology and function of UTP23, its potential as a drug target, and its potential as a biomarker for small subunit processes.

Biography of UTP23

UTP23 is a protein that is expressed in many different cell types, including neurons, muscle cells, and immune cells. It is a small subunit of the processome and is involved in various cellular processes, including intracellular signaling, protein folding, and transport.

UTP23 is composed of a single polypeptide chain that is approximately 110 amino acids in length. It has a unique structure, with a catalytic core that is composed of a single domain that contains a nucleotide exchange site and a hyperfarnesylated cysteine 鈥嬧?媟esidue. The cysteine 鈥嬧?媟esidue is located at the N-terminus of the protein and is known to be a target for small molecule inhibitors.

Function of UTP23

UTP23 is involved in various cellular processes that are critical for cell survival and function. One of its key functions is involved in intracellular signaling. UTP23 is a component of the protein complex known as the adapter-protein complex, which is involved in the regulation of intracellular signaling pathways. This protein complex is composed of multiple proteins, including AP-1, a transcription factor that is involved in the regulation of gene expression, and UTP23, which is involved in the regulation of protein interactions and intracellular signaling.

UTP23 is also involved in protein folding and transport. It is a key component of the protein folding machinery, which is responsible for the regulation of protein structure and function. UTP23 helps to ensure that properly folded proteins are transported to their final destinations in the cell.

Potential Drug Target

UTP23 has been identified as a potential drug target due to its unique structure and function. The cysteine 鈥嬧?媟esidue on UTP23 is known to be a target for small molecule inhibitors, making it an attractive target for drug development.

In fact, several studies have shown that UTP23 is a sensitive target for small molecule inhibitors, including inhibitors of the protein kinase CK2, which is involved in cell signaling. These inhibitors have been shown to inhibit UTP23 activity and to reduce the formation of the protein -protein interaction network that is composed of UTP23 and its interacting partners.

UTP23 has also been shown to be involved in the regulation of cell growth and survival. Studies have shown that UTP23 is involved in the regulation of cell cycle progression, cell survival, and apoptosis.

Potential Biomarkers

UTP23 has also been identified as a potential biomarker for various diseases, including cancer. Its unique structure and function make it an attractive target for diagnostic tools and therapies.

For example, studies have shown that UTP23 is involved in the regulation of

Protein Name: UTP23 Small Subunit Processome Component

Functions: Involved in rRNA-processing and ribosome biogenesis

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