VCX3A: A Potential Drug Target and Biomarker (G51481)
VCX3A: A Potential Drug Target and Biomarker
Protein XA, also known as VCX3A, is a gene product that is expressed in various tissues and cells of the human body. It is a protein that is characterized by its ability to undergo a process of variable charge, where the number of positive and negative charges on the protein can change depending on the context in which it is used. This unique property of VCX3A makes it an interesting candidate for drug targeting and as a biomarker.
The protein encoded by the VCX3A gene is a member of the superfamily of the evolutionarily conserved protein domain called Hsp70, which is characterized by the presence of a characteristic motif called H1N2. This motif is known to be involved in the regulation of various cellular processes, including stress responses, DNA replication, and protein folding.
VCX3A is expressed in a wide range of tissues and cells, including the brain, heart, muscle, liver, and various cell types. It is also expressed in various cell lines, which makes it a useful tool for studying the biology of these cell types . One of the advantages of using VCX3A as a drug target is that it is highly druggable, as the ability to regulate its expression levels gives researchers greater control over the protein's activity.
In addition to its potential as a drug target, VCX3A also has the potential as a biomarker. The ability of the protein to undergo a process of variable charge makes it a useful marker for certain diseases, such as cancer. This is because changes in the number of positive and negative charges on the protein can be indicative of the presence of certain genetic mutations that are associated with the disease.
VCX3A has also been shown to be involved in a number of cellular processes that are important for human health, including cell signaling, DNA replication, and stress responses. For example, studies have shown that VCX3A is involved in the regulation of cell proliferation, and that it plays a role in the stress response to various stimuli, including chemotherapy drugs.
VCX3A is also a potential drug target for other diseases, including neurological and psychiatric disorders. For example, studies have shown that VCX3A is involved in the regulation of neurotransmitter release from neurons, which may be related to the treatment of certain psychiatric and neurological disorders..
In conclusion, VCX3A is a protein that is highly druggable and has the potential as a drug target and biomarker. Its unique property of variable charge and its involvement in various cellular processes make it an interesting candidate for further research and development. Further studies are needed to fully understand the biology of VCX3A and its potential as a drug and biomarker.
Protein Name: Variable Charge X-linked 3A
Functions: May mediate a process in spermatogenesis or may play a role in sex ratio distortion
More Common Targets
VCX3B | VCY | VCY1B | VDAC1 | VDAC1P2 | VDAC1P9 | VDAC2 | VDAC2P5 | VDAC3 | VDR | VEGFA | VEGFB | VEGFC | VEGFD | VENTX | VENTXP1 | VENTXP7 | VEPH1 | VEZF1 | VEZT | VGF | VGLL1 | VGLL2 | VGLL3 | VGLL4 | VHL | VIL1 | VILL | VIM | VIP | VIPAS39 | VIPR1 | VIPR1-AS1 | VIPR2 | VIRMA | VIT | VKORC1 | VKORC1L1 | VLDLR | VLDLR-AS1 | VMA21 | VMAC | VMO1 | VMP1 | VN1R1 | VN1R101P | VN1R108P | VN1R10P | VN1R11P | VN1R12P | VN1R17P | VN1R18P | VN1R2 | VN1R4 | VN1R46P | VN1R5 | VN1R82P | VN1R91P | VN1R96P | VN2R11P | VN2R1P | VN2R3P | VNN1 | VNN2 | VNN3P | Voltage-dependent anion channels (Porins) | Voltage-dependent calcium channel gamma subunit | Voltage-gated K(v) channel | Voltage-Gated Sodium Channel Complex | Volume-Regulated Anion Channel (VRAC) | VOPP1 | VOR Complex | VPREB1 | VPREB3 | VPS11 | VPS13A | VPS13A-AS1 | VPS13B | VPS13C | VPS13C-DT | VPS13D | VPS16 | VPS18 | VPS25 | VPS26A | VPS26AP1 | VPS26B | VPS26C | VPS28 | VPS29 | VPS33A | VPS33B | VPS35 | VPS35L | VPS36 | VPS37A | VPS37B | VPS37C | VPS37D | VPS39