VN1R108P: A Drug Target / Disease Biomarker (G100312850)

Target Name: VN1R108P

NCBI ID: G100312850

Other Name(s): Vomeronasal 1 receptor 108 pseudogene | vomeronasal 1 receptor 108 pseudogene

VN1R108P: A Drug Target / Disease Biomarker

VN1R108P is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its full name is vasopressin receptor type 1, subtype R1 (V1R1), and it is a member of the G protein-coupled receptor (GPCR) family. GPCR is a large family of transmembrane proteins that play a crucial role in cellular signaling, including sensory perception, neurotransmission, and hormone signaling.

VN1R108P is a 14 kDa protein that is expressed in the brain, heart, and kidneys. It is highly expressed in the brain, where it is found in the basal ganglia, the midbrain, and the diencephalon. In the heart, it is expressed in the cardiac muscle and in the pericardium. In the kidneys, it is found in the podocytes.

One of the unique features of VN1R108P is its localization to the intercellular junctions, also known as tight junctions. These junctions are specialized structures that mediate the movement of water and solutes across the membrane of the endothelial cells, which line the blood vessels. VN1R108P is thought to play a role in regulating the movement of water and solutes across the membrane of these cells, which may be important for various physiological processes, including blood pressure and water balance.

Another important function of VN1R108P is its role in neurotransmission. This protein is thought to be involved in the transmission of neurotransmitters, such as dopamine and neurotensin, across the synaptic membrane of neurons. It is also possible that VN1R108P may play a role in the regulation of neurotransmitter release, by interacting with specific transmembrane proteins.

In addition to its role in neurotransmission, VN1R108P is also thought to be involved in the regulation of ion channels. This protein is expressed in the brain and is thought to play a role in the regulation of the voltage-dependent ion channels, which are responsible for the rapid movement of ions through the membrane of the endothelial cells.

The function of VN1R108P is not yet fully understood, but it is clear that it is involved in several important physiological processes in the body. Its localization to the intercellular junctions, its role in neurotransmission, and its potential involvement in ion channel regulation suggest that it may be a valuable drug target or biomarker for a variety of neurological and cardiovascular disorders. Further research is needed to fully understand the function of VN1R108P and its potential implications for human health.

Protein Name: Vomeronasal 1 Receptor 108 Pseudogene

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