VCL: A Protein Involved in Cell Signaling Pathways and Disease Development

Target Name: VCL

NCBI ID: G7414

VCL: A Protein Involved in Cell Signaling Pathways and Disease Development

VCL (Vinculin) is a protein that is expressed in various tissues throughout the body. It is a key structural component of the cytoskeleton and is involved in the proper functioning of cells. VCL has also been shown to play a role in the regulation of cell growth, differentiation, and survival.

Recent studies have identified VCL as a potential drug target and biomarker for a variety of diseases. One of the main reasons for this is the fact that VCL has been shown to be involved in the regulation of many different signaling pathways that are involved in the development and progression of disease.

One of the key signaling pathways that is involved in VCL is the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cell survival and growth, and is thought to be involved in the development of many different diseases, including cancer.

Research has shown that VCL is involved in the regulation of the PI3K/Akt signaling pathway in a number of ways. For example, studies have shown that VCL can inhibit the activity of the protein kinase Akt, which is a key component of the PI3K/ Akt signaling pathway. This can lead to the inhibition of the signaling pathway and the suppression of cell growth and survival.

Another signaling pathway that is involved in VCL is the TGF-β signaling pathway. This pathway is involved in the regulation of cell growth and differentiation, and is also thought to be involved in the development of many different diseases.

Research has shown that VCL is involved in the regulation of the TGF-β signaling pathway in a number of ways. For example, studies have shown that VCL can inhibit the activity of the protein kinase 5Tf, which is a key component of the TGF- 尾 signaling pathway. This can lead to the inhibition of the signaling pathway and the suppression of cell growth and differentiation.

In addition to its role in the regulation of the PI3K/Akt and TGF-β signaling pathways, VCL has also been shown to be involved in the regulation of cell adhesion. This is the process by which cells stick together and form tissues.

Research has shown that VCL is involved in the regulation of cell adhesion in a number of ways. For example, studies have shown that VCL can interact with the protein cadherin, which is a key component of cell adhesion. This interaction can lead to the regulation of the formation and maintenance of tight junctions, which are the junctions that form between cells.

In conclusion, VCL is a protein that is involved in the regulation of various signaling pathways that are involved in the development and progression of disease. Its role in the regulation of cell growth, differentiation, and survival makes VCL a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of VCL in the regulation of disease.

Protein Name: Vinculin

Functions: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion

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