UTP6: A Potential Drug Target and Biomarker for Hepatocellular Carcinoma

Target Name: UTP6

NCBI ID: G55813

UTP6: A Potential Drug Target and Biomarker for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with the majority of cases resulting from the development of HCC due to the expression of oncogenic viruses, such as hepatitis B and C. In addition to viral infections, environmental factors, such as exposure to chemicals and radiation, can also contribute to the development of HCC.

One of the key proteins involved in the development and progression of HCC is the hepatocellular carcinoma-associated antigen (HCA)66. HCA66 is a glycoprotein that is expressed in the liver and has been shown to be associated with the development and progression of HCC.

Recent studies have identified UTP6, a protein that is highly expressed in the liver and has been shown to interact with HCA66, as a potential drug target and biomarker for HCC. UTP6 has been shown to inhibit the growth of HCC cells in cell culture and animal models, and has been shown to reduce the development of HCC in animal models of HCC.

In addition to its potential as a drug target, UTP6 has also been identified as a potential biomarker for HCC. Studies have shown that UTP6 levels are significantly elevated in the liver tissue of individuals with HCC, and that higher UTP6 levels are associated with poorer prognosis in HCC patients.

The identification of UTP6 as a potential drug target and biomarker for HCC makes it an attractive target for researchers to investigate further. Further studies are needed to fully understand the mechanisms of UTP6's role in the development and progression of HCC, as well as its potential as a drug and biomarker.

In conclusion, UTP6 is a protein that has been identified as a potential drug target and biomarker for HCC. Further studies are needed to fully understand its role in the development and progression of HCC and its potential as a therapeutic agent.

Protein Name: UTP6 Small Subunit Processome Component

Functions: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA

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