ARHGAP5: A Potential Drug Target Or Biomarker (G394)
ARHGAP5: A Potential Drug Target Or Biomarker
ARHGAP5 (p105 RhoGAP) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and intestines. It is a member of the Rho GTPase family, which is a group of proteins that play a critical role in cell signaling and cytoskeletal organization.
One of the unique features of ARHGAP5 is its ability to interact with other proteins, including RhoA, which is a GTPase that is involved in the regulation of cell signaling pathways. This interaction between ARHGAP5 and RhoA makes ARHGAP5 a potential drug target or biomarker for a variety of diseases.
ARHGAP5 has been shown to be involved in a number of different signaling pathways, including the regulation of cell proliferation, differentiation, and survival. It has been shown to play a role in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
One of the potential benefits of targeting ARHGAP5 is its potential to disrupt the signaling pathways that are driven by this protein. This could lead to a variety of potential therapeutic effects, including the inhibition of cancer cell growth, the reduction of neurodegeneration, and the improvement of autoimmune disorders.
In addition to its potential therapeutic applications, ARHGAP5 is also a valuable research tool for the study of cell signaling pathways. Its structure and function have been studied extensively, and a wealth of literature has been published on its various roles in these fields.
Overall, ARHGAP5 is a protein that holds great promise as a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role in cell signaling pathways and its potential therapeutic applications.
Protein Name: Rho GTPase Activating Protein 5
Functions: GTPase-activating protein for Rho family members (PubMed:8537347)
More Common Targets
ARHGAP5-AS1 | ARHGAP6 | ARHGAP8 | ARHGAP9 | ARHGDIA | ARHGDIB | ARHGDIG | ARHGEF1 | ARHGEF10 | ARHGEF10L | ARHGEF11 | ARHGEF12 | ARHGEF15 | ARHGEF16 | ARHGEF17 | ARHGEF18 | ARHGEF19 | ARHGEF2 | ARHGEF25 | ARHGEF26 | ARHGEF26-AS1 | ARHGEF28 | ARHGEF3 | ARHGEF33 | ARHGEF34P | ARHGEF35 | ARHGEF37 | ARHGEF38 | ARHGEF38-IT1 | ARHGEF39 | ARHGEF4 | ARHGEF40 | ARHGEF5 | ARHGEF6 | ARHGEF7 | ARHGEF7-AS1 | ARHGEF9 | ARID1A | ARID1B | ARID2 | ARID3A | ARID3B | ARID3C | ARID4A | ARID4B | ARID5A | ARID5B | ARIH1 | ARIH2 | ARIH2OS | ARIH2P1 | ARL1 | ARL10 | ARL11 | ARL13A | ARL13B | ARL14 | ARL14EP | ARL14EP-DT | ARL14EPL | ARL15 | ARL16 | ARL17A | ARL17B | ARL2 | ARL2-SNX15 | ARL2BP | ARL2BPP2 | ARL3 | ARL4A | ARL4AP2 | ARL4C | ARL4D | ARL5A | ARL5AP4 | ARL5B | ARL5C | ARL6 | ARL6IP1 | ARL6IP1P2 | ARL6IP4 | ARL6IP5 | ARL6IP6 | ARL8A | ARL8B | ARL9 | ARLNC1 | ARMC1 | ARMC10 | ARMC12 | ARMC2 | ARMC3 | ARMC5 | ARMC6 | ARMC7 | ARMC8 | ARMC9 | ARMCX1 | ARMCX2 | ARMCX3