FAM3B: A Drug Target / Disease Biomarker (G54097)

Target Name: FAM3B

NCBI ID: G54097

FAM3B: A Drug Target / Disease Biomarker

FAM3B, also known as FAM3B2, is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The FAM3B gene is located on chromosome 16 and encodes for a protein known as FAM3B, which is a member of the superfamily of FAM/POM-related proteins.

The protein encoded by the FAM3B gene has four known functions:

1. Binding to DNA: FAM3B has been shown to interact with DNA and can modulate gene expression in response to DNA damage.
2. Cell survival: FAM3B has been shown to promote cell survival and has been linked to cancer progression.
3. Cell signaling: FAM3B has been shown to participate in cell signaling pathways, including the TGF-β pathway.
4. Cell adhesion: FAM3B has been shown to be involved in cell adhesion and has been linked to various diseases, including neurodegenerative disorders.

FAM3B has also been shown to play a role in several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. In addition, FAM3B has also been linked to various autoimmune disorders, including rheumatoid arthritis, multiple sclerosis, and psoriasis.

FAM3B has also been shown to be involved in the development and progression of certain cancers, including breast cancer, ovarian cancer, and colorectal cancer.

The potential drug target for FAM3B is based on its involvement in several disease processes, including its role in cell signaling, cell adhesion, and cancer progression. Additionally, FAM3B has also been shown to interact with DNA and has been linked to various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Research has also shown that FAM3B can be targeted by small molecules, including inhibitors of its downstream signaling pathways, such as the TGF-β pathway. Additionally, FAM3B has also been shown to have a role in regulating cellular processes that are important for cancer progression, such as cell migration and invasion.

In conclusion, FAM3B is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its functions as a protein have been shown to include binding to DNA, promoting cell survival, participating in cell signaling pathways, and regulating cellular processes that are important for cancer progression. Further research is needed to fully understand the potential of FAM3B as a drug target or biomarker.

Protein Name: FAM3 Metabolism Regulating Signaling Molecule B

Functions: Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner

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