FAM90A1: A Potential Drug Target and Biomarker for Family with Sequence Similarity 90 Member A1

Target Name: FAM90A1

NCBI ID: G55138

Other Name(s): family with sequence similarity 90 member A1 | FAM90A1 variant 1 | Protein FAM90A1 | F90A1_HUMAN | Family with sequence similarity 90 member A1, transcript variant 1

FAM90A1: A Potential Drug Target and Biomarker for Family with Sequence Similarity 90 Member A1

Sequence similarity 90 member A1 (FAM90A1) is a gene that has been identified in various organisms, including humans. It is a member of the superfamily I, also known as the I-type water-splitting domain containing 灏?-sheet containing proteins. FAM90A1 has been shown to play a critical role in various cellular processes, including DNA replication, transcription, and protein-protein interactions. Therefore, it is not surprising that it has also been identified as a potential drug target and biomarker.

FAM90A1 and its Functions

FAM90A1 is a 21-kDa protein that is expressed in various tissues and organs, including brain, heart, skeletal muscles, and organs. It is composed of a unique N-terminal domain that contains a conserved 灏?-sheet, as well as a C-terminal domain that is involved in protein-protein interactions and a central actin-like domain.

The N-terminal domain of FAM90A1 is characterized by a unique 灏?-sheet that is composed of 12 conserved amino acids. This 灏?-sheet is known as the \"I-type water-splitting domain\" (2) and is responsible for water splitting, which is a critical process in the DNA replication and transcription.

The C-terminal domain of FAM90A1 is composed of 19 amino acids and is involved in protein-protein interactions. It is known as the \"core region\" (3) and is thought to play a role in regulating the stability and localization of the N-terminal domain.

FAM90A1 and Disease

FAM90A1 has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. For example, studies have shown that FAM90A1 is overexpressed in various cancer tissues and that it is involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its involvement in disease, FAM90A1 has also been shown to be a potential drug target. Studies have shown that FAM90A1 can interact with various drugs, including small molecules, peptides, and antibodies, and that these interactions can lead to changes in cellular behavior and promote the development of certain diseases.

FAM90A1 as a Biomarker

FAM90A1 has also been shown to be a potential biomarker for various diseases. For example, studies have shown that FAM90A1 is expressed in the brains of individuals with Alzheimer's disease and that its levels are correlated with the severity of the disease. Additionally, studies have shown that FAM90A1 is expressed in the brains of individuals with Parkinson's disease and that its levels are correlated with the severity of the disease.

FAM90A1 as a Drug Target

FAM90A1 has been shown to be a potential drug target for various diseases. For example, studies have shown that FAM90A1 can interact with various drugs, including small molecules, peptides, and antibodies, and that these interactions can lead to changes in cellular behavior and promote the development of certain diseases.

Conclusion

In conclusion, FAM90A1 is a gene that has been identified in various organisms, including humans. It is a member of the superfamily I, also known as the I-type water-splitting domain containing 灏?-sheet containing proteins, and has been shown to play a critical role in various cellular processes, including DNA replication, transcription, and protein-protein interactions. FAM90A1 is also a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Further research is needed to fully understand the role of FAM90A1 in disease and to develop effective treatments.

Protein Name: Family With Sequence Similarity 90 Member A1

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