FBLN2: A Potential Drug Target for Neurodegenerative Disorders
FBLN2: A Potential Drug Target for Neurodegenerative Disorders
FBLN2 (FBLN2 variant 1) is a gene that has been identified as a potential drug target or biomarker for the treatment of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions. The FBLN2 gene is located on chromosome 12 and encodes for a protein known as FBLN2, which is a key regulator of the brain-cell adhesion molecule PDGFR-尾.
The PDGFR-尾 protein is involved in several important cellular processes in the brain, including the formation and maintenance of neural connections, as well as the regulation of the brain's response to external stimuli. dysfunction in PDGFR-尾 has been linked to the development of a number of neurodegenerative conditions, including Alzheimer's disease and Parkinson's disease.
Research has also suggested that dysfunction in PDGFR-尾 may be involved in the development of other neurological disorders, including multiple sclerosis and amyotrophic lateral sclerosis (ALS).
In addition to its potential role in the development of neurodegenerative conditions, PDGFR-尾 has also been shown to play a key role in the regulation of various cellular processes in the brain, including cell survival, migration, and synaptic formation.
The FBLN2 gene has also been shown to be involved in the regulation of several important cellular processes in the brain, including the formation and maintenance of neural connections, as well as the regulation of the brain's response to external stimuli. dysfunction in FBLN2 has been linked to the development of a number of neurological disorders, including Alzheimer's disease and Parkinson's disease.
Research has also suggested that dysfunction in FBLN2 may be involved in the development of other neurological disorders, including multiple sclerosis and ALS.
In addition to its potential role in the development of neurodegenerative conditions, FBLN2 has also been shown to play a key role in the regulation of various cellular processes in the brain, including cell survival, migration, and synaptic formation.
The FBLN2 gene has also been shown to be involved in the regulation of several important cellular processes in the brain, including the formation and maintenance of neural connections, as well as the regulation of the brain's response to external stimuli. dysfunction in FBLN2 has been linked to the development of a number of neurological disorders, including Alzheimer's disease and Parkinson's disease.
Research has also suggested that dysfunction in FBLN2 may be involved in the development of other neurological disorders, including multiple sclerosis and ALS.
Recent studies have suggested that FBLN2 may be a promising drug target for the treatment of neurodegenerative conditions. For example, research has shown that inhibition of FBLN2 can lead to the reversal of cognitive and behavioral deficits in animal models of Alzheimer's disease. Similarly, inhibition of FBLN2 has been shown to lead to the improvement of motor function in animal models of Parkinson's disease.
In addition to its potential role in the treatment of neurodegenerative conditions, FBLN2 has also been shown to have potential as a biomarker for the diagnosis of these conditions. For example, research has shown that FBLN2 levels are often reduced in the brains of individuals with Alzheimer's disease, and that these levels are increased in the brains of individuals with Parkinson's disease.
FBLN2 has also been shown to be involved in the regulation of several important cellular processes in the brain, including cell survival, migration, and synaptic formation. dysfunction in FBLN2 has been linked to the development
Protein Name: Fibulin 2
Functions: Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108)
More Common Targets
FBLN5 | FBLN7 | FBN1 | FBN2 | FBN3 | FBP1 | FBP2 | FBRS | FBRSL1 | FBXL12 | FBXL13 | FBXL14 | FBXL15 | FBXL16 | FBXL17 | FBXL18 | FBXL19 | FBXL19-AS1 | FBXL2 | FBXL20 | FBXL21P | FBXL22 | FBXL3 | FBXL4 | FBXL5 | FBXL6 | FBXL7 | FBXL8 | FBXL9P | FBXO10 | FBXO11 | FBXO15 | FBXO16 | FBXO17 | FBXO2 | FBXO21 | FBXO22 | FBXO24 | FBXO25 | FBXO27 | FBXO28 | FBXO3 | FBXO30 | FBXO31 | FBXO32 | FBXO33 | FBXO34 | FBXO36 | FBXO38 | FBXO39 | FBXO4 | FBXO40 | FBXO41 | FBXO42 | FBXO43 | FBXO44 | FBXO45 | FBXO46 | FBXO47 | FBXO48 | FBXO5 | FBXO6 | FBXO7 | FBXO8 | FBXO9 | FBXW10 | FBXW10B | FBXW11 | FBXW12 | FBXW2 | FBXW4 | FBXW4P1 | FBXW5 | FBXW7 | FBXW7-AS1 | FBXW8 | FBXW9 | Fc-gamma Receptor (FCGR) | FCAMR | FCAR | FCER1A | FCER1G | FCER2 | FCF1 | FCF1P11 | FCF1P2 | FCF1P5 | FCGBP | FCGR1A | FCGR1BP | FCGR1CP | FCGR2A | FCGR2B | FCGR2C | FCGR3A | FCGR3B | FCGRT | FCHO1 | FCHO2 | FCHSD1