FCGR2A: A Potential Drug Target and Biomarker for IgG Fc Receptor II-a

Target Name: FCGR2A

NCBI ID: G2212

FCGR2A: A Potential Drug Target and Biomarker for IgG Fc Receptor II-a

IgG Fc receptor II-a (FCGR2A) is a type of immunoglobulin or antibody that plays a crucial role in the immune system. It is a protein that is expressed in various tissues and cells in the body, including the liver, spleen, and bones. FCGR2A is also known as CD11b, and its function is to interact with the IgG Fc receptor II-a, which is a protein that is expressed in many tissues and cells throughout the body.

The FCGR2A gene has been identified and its function is well understood. It is a single transmembrane protein that contains a N-terminus that is involved in the formation of an interaction complex with the IgG Fc receptor II-a. This interaction between the two proteins is critical for the function of FCGR2A.

FCGR2A has been shown to play a role in various physiological processes in the body, including immune responses, inflammation, and metabolism. For example, FCGR2A has been shown to be involved in the regulation of inflammation and has been shown to play a role in the development of certain diseases, such as rheumatoid arthritis and insulin-dependent diabetes mellitus.

In addition to its role in the immune system, FCGR2A has also been shown to play a role in the regulation of inflammation in the body. It has been shown to be involved in the regulation of the production of pro-inflammatory cytokines, such as TNF-alpha, IL-1, and IL-6. It has also been shown to play a role in the regulation of the production of anti-inflammatory cytokines, such as IL-10.

FCGR2A has also been shown to play a role in the regulation of cellular signaling pathways. It has been shown to be involved in the regulation of several signaling pathways, including the TGF-beta pathway and the PI3K/Akt pathway. These signaling pathways are important for the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

In conclusion, FCGR2A is a protein that is involved in various physiological processes in the body. Its function is well understood, and it has been shown to play a role in the regulation of the immune system, inflammation, and cellular signaling pathways. As a result, FCGR2A may be a potential drug target and biomarker for various diseases. Further research is needed to fully understand its role and potential as a drug.

Protein Name: Fc Gamma Receptor IIa

Functions: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens

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