Target Name: FCHO2
NCBI ID: G115548
Other Name(s): F-BAR domain only protein 2 (isoform a) | FCH and mu domain containing endocytic adaptor 2 | FCH and mu domain containing endocytic adaptor 2, transcript variant 1 | FCH domain only protein 2 | FCH domain only 2 | FCHO2 variant 1 | FCHO2_HUMAN | F-BAR domain only protein 2

FCHO2: A Potential Drug Target and Biomarker for Various Diseases

FCHO2 (F-BAR domain only protein 2) is a protein that is expressed in most tissues of the body. It is a member of the BAR family of proteins, which are known for their ability to interact with various molecules, including small molecules, peptides, and drugs. In this article, we will discuss FCHO2 as a potential drug target and its potential as a biomarker for various diseases.

FCHO2 is a 120-kDa protein that is expressed in most tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. It is primarily localized to the endoplasmic reticulum (ER), where it can interact with various membrane receptors and ion channels. FCHO2 is also known for its role in cell signaling, as it has been shown to play a role in the regulation of ion channels, including the K channels that are responsible for the rapid transport of nutrients and ions into cells.

FCHO2 has also been shown to play a role in the regulation of gene expression, which is the process by which cells express the instructions for making proteins. This is because FCHO2 has also been shown to interact with various transcription factors, which are proteins that are responsible for transmitting genetic information from the DNA to the RNA that is used to create proteins. These interactions between FCHO2 and transcription factors have been shown to play a role in the regulation of various gene expression patterns, including the expression of pain-related genes.

FCHO2 has also been shown to have a role in the regulation of cellular stress responses. When cells are exposed to stress, they are able to adapt to the conditions and survive by changing their behavior and morphology in a variety of ways. to play a role in the regulation of cellular stress responses by interacting with various stress-responsive signaling pathways.

FCHO2 has also been shown to have a role in the regulation of cellular metabolism. FCHO2 has been shown to interact with various enzymes that are involved in cellular metabolism, including the citrate synthase enzyme, which is responsible for the production of citrate, a compound that is involved in the regulation of various cellular processes, including the production of energy.

FCHO2 has also been shown to play a role in the regulation of cell signaling pathways that are involved in the development and progression of various diseases, including cancer. For example, FCHO2 has been shown to play a role in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cellular signaling pathways that are involved in cancer progression.

In addition to its role in cell signaling, FCHO2 has also been shown to have potential as a drug target. Because FCHO2 is involved in the regulation of various cellular processes that are involved in the development and progression of various diseases, it is a potential target for small molecules that can modulate these processes. For example, FCHO2 has been shown to be involved in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cellular signaling pathways that are involved in cancer progression. Therefore, inhibitors of the PI3K/Akt signaling pathway, which have been shown to have potential as anti-cancer agents, may be effective in targeting FCHO2 and inhibiting its function as a drug.

FCHO2 has also been shown to have potential as a biomarker for various diseases. For example, FCHO2 has been shown to be involved in the regulation of cellular stress responses, which can be used as a biomarker for stress-related diseases, such as cancer, heart disease, and neurodegenerative diseases. Additionally, FCHO2

Protein Name: FCH And Mu Domain Containing Endocytic Adaptor 2

Functions: Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor

More Common Targets

FCHSD1 | FCHSD2 | FCMR | FCN1 | FCN2 | FCN3 | FCRL1 | FCRL2 | FCRL3 | FCRL4 | FCRL5 | FCRL6 | FCRLA | FCRLB | FCSK | FDCSP | FDFT1 | FDPS | FDPSP2 | FDPSP4 | FDPSP5 | FDPSP6 | FDPSP7 | FDX1 | FDX2 | FDXACB1 | FDXR | FECH | FEM1A | FEM1AP4 | FEM1B | FEM1C | FEN1 | FENDRR | FER | FER1L4 | FER1L5 | FER1L6 | FER1L6-AS1 | FER1L6-AS2 | FERD3L | FERMT1 | FERMT2 | FERMT3 | Ferritin | FES | Fetal Hemoglobin (HbF) | FETUB | FEV | FEZ1 | FEZ2 | FEZF1 | FEZF1-AS1 | FEZF2 | FFAR1 | FFAR2 | FFAR3 | FFAR4 | FGA | FGB | FGD1 | FGD2 | FGD3 | FGD4 | FGD5 | FGD5-AS1 | FGD5P1 | FGD6 | FGF1 | FGF10 | FGF10-AS1 | FGF11 | FGF12 | FGF12-AS2 | FGF13 | FGF13-AS1 | FGF14 | FGF14-AS1 | FGF14-AS2 | FGF14-IT1 | FGF16 | FGF17 | FGF18 | FGF19 | FGF2 | FGF20 | FGF21 | FGF22 | FGF23 | FGF3 | FGF4 | FGF5 | FGF6 | FGF7 | FGF7P3 | FGF7P5 | FGF7P6 | FGF8 | FGF9 | FGFBP1