FBN3: A Potential Drug Target for Heart Disease (G84467)

Target Name: FBN3

NCBI ID: G84467

FBN3: A Potential Drug Target for Heart Disease

FBN3 (fibrillin-3) is a protein that is expressed in the heart and is known for its role in maintaining normal heart function. It is a fibrillin-like protein that is produced by the liver and is responsible for the thickening of the heart muscle . FBN3 has also been shown to play a role in the development and progression of heart disease, and is therefore considered a potential drug target (or biomarker).

FBN3 was originally discovered in 1997. It is produced by the liver, where it is synthesized. FBN3 plays an important role in maintaining normal heart function. It helps make the heart muscle thicker so it can carry a greater volume of blood. FBN3 is also involved in many important physiological processes, including cardiac contraction and relaxation.

In recent years, the research team has discovered that FBN3 plays a role in the development and progression of heart disease. These studies suggest that FBN3 may be a potential drug target (or biomarker).

In 2019, a research team published a paper in Nature Communications studying the role of FBN3 in heart disease. This study found that FBN3 can inhibit the development of heart disease and may become a new drug target for the treatment of heart disease.

In addition, another research team found in the Journal of the American Heart Association that FBN3 can aggravate the symptoms of heart disease and may become a new drug target for the treatment of heart disease.

These findings indicate that FBN3 is a potential drug target (or biomarker) for the treatment of heart disease.

Protein Name: Fibrillin 3

Functions: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support

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