FBXO47: A Potential Drug Target and Biomarker (G494188)

Target Name: FBXO47

NCBI ID: G494188

Other Name(s): F-box only protein 47 | F-box protein 47 | FBX47_HUMAN

FBXO47: A Potential Drug Target and Biomarker

FBXO47 is a protein that is expressed in various tissues and cells of the human body. Its full name is F-box only protein 47, and it is a member of the F-box protein family, which is a family of proteins that are known for their unique structural features. This protein is of particular interest to researchers because of its potential role as a drug target or biomarker.

Diseases and Therapies

One of the most promising aspects of FBXO47 is its potential as a drug target. FBXO47 has been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that FBXO47 is overexpressed in various types of cancer, including breast, lung, and ovarian cancer. Additionally, research has suggested that FBXO47 may be a potential biomarker for neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Another potential use of FBXO47 as a drug target is its role in the development of neurodegenerative diseases. FBXO47 has been shown to promote the formation of neurofibrillary tangles, which are a hallmark of neurodegenerative diseases, in mouse models of Alzheimer's disease. This suggests that FBXO47 may be a useful target for therapies that are designed to prevent or reverse the development of these diseases.

Another potential use of FBXO47 as a drug target is its role in autoimmune disorders. FBXO47 has been shown to play a role in the development of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. This suggests that FBXO47 may be a useful target for therapies that are designed to treat these disorders.

FBXO47 as a Biomarker

FBXO47 has also been shown to serve as a potential biomarker for a variety of diseases. For example, studies have shown that FBXO47 is overexpressed in various types of cancer, including breast, lung, and ovarian cancer. This suggests that FBXO47 may be a useful biomarker for these diseases, and that it may help doctors to diagnose and monitor the effectiveness of treatments.

In addition to its potential as a biomarker, FBXO47 has also been shown to serve as a potential therapeutic target in cancer. Studies have shown that FBXO47 can inhibit the growth of cancer cells in a variety of settings, including in cell culture and in animal models of cancer. This suggests that FBXO47 may be a useful target for cancer therapies that are designed to inhibit the growth of cancer cells.

Conclusion

In conclusion, FBXO47 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Its unique structural features and its role in the development of various diseases make it an attractive target for researchers to study. Further studies are needed to determine the full potential of FBXO47 as a drug target and biomarker.

Protein Name: F-box Protein 47

Functions: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation

More Common Targets