FCER2: Multiple Functions and Potential Drug Target in Cellular Signaling
FCER2: Multiple Functions and Potential Drug Target in Cellular Signaling
FCER2 (fucosinyl-containing endoplasmic reticulum-associated protein 2) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the endoplasmic reticulum-associated protein (ERP) family, which includes a variety of transmembrane proteins that play important roles in cellular signaling and organization.
One of the functions of FCER2 is to interact with other proteins that are expressed in the endoplasmic reticulum, including the protein known as p110R1. The p110R1 protein is a member of the superfamily of coiled-coil transmembrane proteins, which are characterized by the presence of a coiled-coil region that can interact with other proteins.
FCER2 has been shown to play a role in the regulation of cellular signaling pathways, including the negative signaling pathway that is involved in the regulation of cell growth and differentiation. This pathway is known as the TGF-β pathway, and it is involved in the development and maintenance of tissues and organs, as well as in the regulation of cell survival and death.
FCER2 has also been shown to be involved in the regulation of the Wnt signaling pathway, which is involved in the regulation of cell growth and differentiation during development. Wnt signaling is a critical pathway that is involved in the development and maintenance of tissues and organs, and it is often disrupted in a variety of diseases, including cancer.
FCER2 has also been shown to play a role in the regulation of theNotch signaling pathway, which is involved in the regulation of cell survival and development. Notch signaling is a critical pathway that is involved in the regulation of cell survival and development, and it is often disrupted in a variety of diseases, including neurodegenerative diseases.
In addition to its role in the regulation of cellular signaling pathways, FCER2 has also been shown to play a role in the regulation of cellular structure and organization. FCER2 is a member of the reticulon family of proteins, which is involved in the regulation of cell structure and organization.
FCER2 has also been shown to play a role in the regulation of cellular function, including the regulation of cell adhesion and the regulation of cell signaling pathways. FCER2 is a member of the cadherin family of transmembrane proteins, which is involved in the regulation of cell adhesion and the regulation of cell signaling pathways.
In conclusion, FCER2 is a protein that is involved in a variety of cellular processes that are important for the regulation of cell growth, differentiation, and survival. It is a member of the ERP family and the cadherin family of transmembrane proteins, and it has been shown to play a role in the regulation of cellular signaling pathways, including the negative signaling pathway that is involved in the regulation of cell growth and differentiation, the Wnt signaling pathway, and the Notch signaling pathway. FCER2 is also involved in the regulation of cellular structure and organization, including the regulation of cell adhesion and the regulation of cell signaling pathways. Given its involvement in these processes, FCER2 is a potential drug target and a biomarker for a variety of diseases.
Protein Name: Fc Epsilon Receptor II
Functions: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells (PubMed:2167225). On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway (PubMed:7544003)
More Common Targets
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