FBXW12: A Potential Drug Target and Biomarker (G285231)

Target Name: FBXW12

NCBI ID: G285231

FBXW12: A Potential Drug Target and Biomarker

FBXW12, also known as F-box and WD-40 domain-containing protein 12, is a protein that has been identified as a potential drug target and biomarker. FBXW12 is a 23-kDa protein that is expressed in various tissues and organs, including muscle, heart, brain, and pancreas. It plays a role in the regulation of cellular processes, including cell adhesion, migration, and signaling pathways.

The F-box gene is a known gene that is involved in the development and maintenance of various proteins, including FBXW12. The WD-40 domain is a known protein domain that is found in a variety of proteins, including the F-box protein. The domain is known for its ability to interact with various chemical entities, including small molecules, peptides, and other proteins.

The Potential Drug Target

FBXW12 has been identified as a potential drug target due to its involvement in various cellular processes that are relevant to the development and treatment of various diseases. One of the potential drug targets for FBXW12 is its role in cell adhesion and migration. FBXW12 has been shown to play a role in the regulation of cell-cell adhesion by promoting the interaction between its F-box domain and the F-actinin protein.

FBXW12 has also been shown to be involved in the regulation of cell migration, which is a critical process for the development and progression of various diseases, including cancer. In addition, FBXW12 has been shown to play a role in the regulation of angiogenesis, which is the process by which new blood vessels are formed.

The Potential Biomarker

FBXW12 has also been identified as a potential biomarker for various diseases. One of the potential applications of FBXW12 as a biomarker is its ability to be expressed and processed from patient samples, such as blood or tissue samples, which can be used to diagnose and monitor various diseases.

For example, FBXW12 has been shown to be involved in the regulation of cancer cell growth and metastasis. In addition, FBXW12 has been shown to play a role in the regulation of inflammation, which is a critical process for the development and progression of various diseases, including cancer.

Conclusion

FBXW12 is a protein that has been identified as a potential drug target and biomarker. Its role in the regulation of cellular processes, including cell adhesion, migration, and signaling pathways makes it an attractive target for the development of new pharmaceuticals for the treatment of various diseases. In addition, its potential as a biomarker for the diagnosis and monitoring of diseases makes it an important tool for the development of new diagnostic tools. Further research is needed to fully understand the role of FBXW12 as a drug target and biomarker.

Protein Name: F-box And WD Repeat Domain Containing 12

Functions: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex

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