FBXL5: A Potential Drug Target for Various Diseases (G26234)
FBXL5: A Potential Drug Target for Various Diseases
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FBXL5 is a protein that is expressed in the human placenta. It is a member of the family of the heat shock protein (HSP) family and is involved in the regulation of various cellular processes that are critical for human health. FBXL5 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
One of the key functions of FBXL5 is its ability to interact with other proteins that are expressed in the placenta, including the protein known as PLTL1. PLTL1 is a protein that is expressed in the placenta and has been shown to play a role in the development and progression of various diseases, including cancer.
Research has suggested that FBXL5 may be a drug target for various diseases, including cancer. One of the reasons for this is the fact that FBXL5 has been shown to interact with PLTL1, which suggests that it may be able to modulate the activity of PLTL1. This could potentially give rise to new treatments for diseases that are currently difficult to treat, such as cancer.
Another potential mechanism by which FBXL5 may be involved in the development and progression of diseases is its role in the regulation of cellular processes that are critical for the development and maintenance of tissues. For example, FBXL5 has been shown to play a role in the regulation of cell division and the production of new cells, which could potentially be relevant to the development of neurodegenerative diseases.
FBXL5 has also been shown to be involved in the regulation of the immune system, which is critical for the defense against infections and other harmful substances. This suggests that it may be involved in the development and progression of autoimmune disorders.
In conclusion, FBXL5 is a protein that is expressed in the human placenta and has been shown to play a role in the regulation of various cellular processes that are critical for human health. Its potential as a drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders makes it an important area of research. Further studies are needed to fully understand the role of FBXL5 in these processes and to develop new treatments for diseases that are currently difficult to treat.
Protein Name: F-box And Leucine Rich Repeat Protein 5
Functions: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued
More Common Targets
FBXL6 | FBXL7 | FBXL8 | FBXL9P | FBXO10 | FBXO11 | FBXO15 | FBXO16 | FBXO17 | FBXO2 | FBXO21 | FBXO22 | FBXO24 | FBXO25 | FBXO27 | FBXO28 | FBXO3 | FBXO30 | FBXO31 | FBXO32 | FBXO33 | FBXO34 | FBXO36 | FBXO38 | FBXO39 | FBXO4 | FBXO40 | FBXO41 | FBXO42 | FBXO43 | FBXO44 | FBXO45 | FBXO46 | FBXO47 | FBXO48 | FBXO5 | FBXO6 | FBXO7 | FBXO8 | FBXO9 | FBXW10 | FBXW10B | FBXW11 | FBXW12 | FBXW2 | FBXW4 | FBXW4P1 | FBXW5 | FBXW7 | FBXW7-AS1 | FBXW8 | FBXW9 | Fc-gamma Receptor (FCGR) | FCAMR | FCAR | FCER1A | FCER1G | FCER2 | FCF1 | FCF1P11 | FCF1P2 | FCF1P5 | FCGBP | FCGR1A | FCGR1BP | FCGR1CP | FCGR2A | FCGR2B | FCGR2C | FCGR3A | FCGR3B | FCGRT | FCHO1 | FCHO2 | FCHSD1 | FCHSD2 | FCMR | FCN1 | FCN2 | FCN3 | FCRL1 | FCRL2 | FCRL3 | FCRL4 | FCRL5 | FCRL6 | FCRLA | FCRLB | FCSK | FDCSP | FDFT1 | FDPS | FDPSP2 | FDPSP4 | FDPSP5 | FDPSP6 | FDPSP7 | FDX1 | FDX2 | FDXACB1