FBLN5: Unlocking the Potential of Potential Drugs (G10516)

Target Name: FBLN5

NCBI ID: G10516

FBLN5: Unlocking the Potential of Potential Drugs

FBLN5 (FBLN5_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. It is a member of the FBLN gene family, which is known for its role in cell-cell adhesion and the development of tissues.

FBLN5 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these processes is not well understood, but it is thought to contribute to the dysfunction and dysfunctionality of these diseases.

One of the key functions of FBLN5 is its role in cell-cell adhesion. This is the process by which cells stick together to form tissues and organs. FBLN5 is thought to help regulate the formation and maintenance of tight junctions, which are the weak bonds that hold cells together.

In neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, FBLN5 has been shown to be involved in the development of neurofibrillary tangles and neurogenic gradients, which are thought to contribute to the dysfunction and death of nerve cells.

FBLN5 has also been shown to be involved in the development and progression of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. In these disorders, the immune system attacks the body's own tissues, leading to inflammation and damage. FBLN5 is thought to contribute to this process by regulating the movement of immune cells into the affected tissue.

Despite its involvement in these diseases, FBLN5 is not a well-studied protein. There are currently no drugs that are specifically designed to target FBLN5. This is because of its widespread expression in the body and the difficulty in finding small, specific molecules that can interact with it.

However, researchers are actively working to develop new drugs that can target FBLN5. This is an important area of research, as the development of new treatments for these diseases is a major priority.

In conclusion, FBLN5 is a protein that is expressed in various tissues of the human body and is thought to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to understand its role in these processes and to develop new treatments for these diseases.

Protein Name: Fibulin 5

Functions: Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108)

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