FBLN7: A Potential Drug Target and Biomarker (G129804)

Target Name: FBLN7

NCBI ID: G129804

FBLN7: A Potential Drug Target and Biomarker

FBLN7 (Msp5) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and blood vessels. It is a member of the Integrin alpha-2 (IAA) family, which is known for its role in cell adhesion and migration.

FBLN7 has been identified as a potential drug target due to its unique structure and its expression in various tissues. The FBLN7 protein is composed of a cytoplasmic domain, a transmembrane domain, and an extracellular domain. The cytoplasmic domain is responsible for the protein's ability to interact with intracellular signaling pathways, while the transmembrane domain is responsible for its ability to interact with the extracellular environment. The extracellular domain is responsible for the protein's ability to interact with other proteins and for its role in cell adhesion and migration.

One of the key features of FBLN7 is its ability to interact with integrins, which are a type of protein that is found on the surface of many cells. Integrins are involved in many different processes in the body, including cell adhesion, migration, and signaling. By interacting with integrins, FBLN7 is able to regulate the movement and behavior of cells, which can be a potential target for drugs.

Another feature of FBLN7 is its expression in various tissues, which suggests that it may be a useful biomarker for certain diseases. For example, FBLN7 has been shown to be expressed in the brain, heart, and blood vessels, which suggests that it may be involved in the development and progression of neurological and cardiovascular diseases. This makes FBLN7 an attractive target for drugs that are designed to treat these conditions.

In addition to its potential drug target properties, FBLN7 also has potential as a biomarker. The expression of FBLN7 has been shown to be associated with the development of certain diseases, including cancer and neurodegenerative diseases. This suggests that FBLN7 may be a useful biomarker for these diseases, and that its levels may be able to be used to diagnose and monitor the progression of these conditions.

Overall, FBLN7 is a protein that has a unique structure and is expressed in various tissues throughout the body. Its ability to interact with integrins and its expression in various tissues make it a potential drug target and a useful biomarker for certain diseases. Further research is needed to fully understand the role of FBLN7 in the body and its potential as a drug and biomarker.

Protein Name: Fibulin 7

Functions: An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation

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