Fiance: A Potential Drug Target for Various Diseases (G2178)

Target Name: FANCE

NCBI ID: G2178

Fiance: A Potential Drug Target for Various Diseases

Fiance (FANCE\\_HUMAN) is a protein that is expressed in human tissues and has been shown to play a role in various physiological processes in the body. Fiance has also been identified as a potential drug target and biomarker for various diseases, making it an attractive target for researchers to study.

Fiance's Role in Signal Transduction

Fiance is a member of the FSHR family, which includes proteins that are involved in the regulation of stem cell proliferation and differentiation. These proteins play a crucial role in ensuring that stem cells maintain their undifferentiated state and are not prone to undergo apoptosis.

Fiance is involved in the regulation of several intracellular signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and maintenance of tissues.

Fiance has been shown to play a role in the regulation of TGF-β signaling by inhibiting the activity of the transcription factor SMAD. This has been shown to result in the inhibition of TGF-β signaling and the maintenance of stem cell undifferentiated state.

Fiance's Role in Disease

Fiance has been identified as a potential drug target for several diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Fiance's potential as a cancer drug target is due to its role in the regulation of cell growth and survival. cancer cells are characterized by uncontrolled cell growth and the ability to evade apoptosis, which allows them to persist and promote the formation of tumors.

Fiance has been shown to play a role in the regulation of cell survival by inhibiting the activity of the transcription factor SMAD, which is a key factor in the regulation of cell apoptosis. This has been shown to result in the inhibition of cancer cell growth and the inhibition of tumor formation.

Fiance's potential as a neurodegenerative disease drug target is due to its role in the regulation of neurotransmitter synthesis and release, as well as its role in the regulation of ion channels and neurotransmitter receptors.

Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterized by the progressive loss of neurotransmitters and the damaged regulation of neurotransmitter release. Fiance's role in the regulation of neurotransmitter synthesis and release suggests that it may be a potential drug target for these diseases.

Fiance's potential as an autoimmune disease drug target is due to its role in the regulation of immune cell function and the regulation of inflammation.

Autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, are characterized by the immune system's overreaction and the production of autoantibodies. Fiance's role in the regulation of immune cell function suggests that it may be a potential drug target for these diseases.

Conclusion

Fiance is a protein that has been shown to play a role in various physiological processes in the body, including the regulation of stem cell proliferation and differentiation, intracellular signaling pathways, and the regulation of cell survival. Its potential as a drug target and biomarker for cancer, neurodegenerative diseases, and autoimmune diseases makes it an attractive target for researchers to study. Further research is needed to fully understand the role of Fiance in the regulation of these diseases and to develop effective treatments.

Protein Name: FA Complementation Group E

Functions: As part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. Required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2

More Common Targets