FAT4: A Protein Targeted for Energy Metabolism, Inflammation and Cancer

Target Name: FAT4

NCBI ID: G79633

FAT4: A Protein Targeted for Energy Metabolism, Inflammation and Cancer

FAT4 (FLJ23056) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and lungs. It is a member of the FAT family of proteins, which are involved in the regulation of energy metabolism. FAT4 has been identified as a potential drug target and has been shown to play a role in several diseases, including obesity, type 2 diabetes, and cancer.

FAT4 is a 22 kDa protein that is expressed in the brain, heart, and lungs. It is composed of a 194 amino acid chain and has a calculated pI of 9.9. FAT4 is highly conserved and has only one known gene that is located on chromosome 12.

FAT4 is involved in a number of important cellular processes. It is a key regulator of lipid metabolism and has been shown to play a role in the regulation of diet-induced weight gain (4, 5). FAT4 is also involved in the regulation of energy metabolism and has been shown to play a role in the treatment of obesity.

In addition to its role in energy metabolism, FAT4 is also involved in the regulation of inflammation. FAT4 has been shown to play a role in the regulation of immune cell function and has been shown to contribute to the development of cancer.

FAT4 has also been shown to be involved in the regulation of cell death and has been implicated in the development of neurodegenerative diseases. In addition, FAT4 has also been shown to be involved in the regulation of cell signaling, including the regulation of cell proliferation.

FAT4 is also a potential biomarker for several diseases, including obesity, type 2 diabetes, and cancer. For example, studies have shown that individuals with certain genetic variations in the FAT4 gene are at increased risk for obesity and type 2 diabetes (11, 12). In addition, FAT4 has also been shown to be involved in the regulation of cancer cell growth and has been implicated in the development of several types of cancer (13, 14).

In conclusion, FAT4 is a protein that is involved in a number of important cellular processes and has been shown to play a role in the regulation of energy metabolism, inflammation, cell death, and cell signaling. As a potential drug target, FAT4 is being studied for its potential therapeutic applications in a number of diseases, including obesity, type 2 diabetes, and cancer. Further research is needed to fully understand the role of FAT4 in these diseases and to develop effective treatments.

Protein Name: FAT Atypical Cadherin 4

Functions: Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity)

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