Target Name: FAM83D
NCBI ID: G81610
Other Name(s): dJ616B8.3 | Protein FAM83D | CHICA | C20orf129 | Spindle protein CHICA | family with sequence similarity 83 member D | Family with sequence similarity 83 member D | spindle protein CHICA | FA83D_HUMAN | DJ616B8.3

FAM83D: A Potential Drug Target for Various Diseases

FAM83D (dJ616B8.3) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The FAM83D gene is located on chromosome 6 and encodes a protein known as FAM83D, which is a key regulator of theNotch signaling pathway. TheNotch signaling pathway is a critical regulatory pathway involved in the development and maintenance of tissues and organs, and is implicated in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Studies have shown that FAM83D is involved in the regulation of various cellular processes, including cell adhesion, migration, and survival. It has also been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key reasons for the interest in FAM83D as a potential drug target or biomarker is its involvement in the regulation of Notch signaling pathway. Notch signaling pathway is a critical regulatory pathway involved in the development and maintenance of tissues and organs, and is implicated in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Therefore, targeting the FAM83D gene has the potential to treat a wide range of diseases that are currently treated with little to no efficacy.

Another reason for the interest in FAM83D is its role in the regulation of cell adhesion and migration. FAM83D has been shown to play a role in the regulation of cell adhesion and migration, which are important processes that are critical for the development and maintenance of tissues and organs. Therefore, targeting the FAM83D gene has the potential to treat a wide range of diseases that are currently treated with little to no efficacy.

In addition to its involvement in the regulation of Notch signaling pathway and cell adhesion and migration, FAM83D has also been shown to play a role in the regulation of cellular processes that are important for the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

FAM83D has also been shown to play a role in the regulation of stem cell proliferation and differentiation. Stem cells are a type of cell that have the potential to develop into any type of cell in the body, and are involved in the development and maintenance of tissues and organs. Therefore, targeting the FAM83D gene has the potential to treat a wide range of diseases that are currently treated with little to no efficacy.

FAM83D has also been shown to play a role in the regulation of the immune system. The immune system is a critical regulatory system that is involved in the defense of the body against a wide range of threats, including cancer, neurodegenerative diseases, and autoimmune disorders. Therefore, targeting the FAM83D gene has the potential to treat a wide range of diseases that are currently treated with little to no efficacy.

In conclusion, FAM83D is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its involvement in the regulation of Notch signaling pathway, cell adhesion, migration, and stem cell proliferation and differentiation, as well as its involvement in the regulation of the immune system, make it an attractive target for drug development. Further studies are needed to confirm its potential as a drug target or biomarker, and to develop safe and effective treatments.

Protein Name: Family With Sequence Similarity 83 Member D

Functions: Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22 (PubMed:18485706)

More Common Targets

FAM83E | FAM83F | FAM83G | FAM83H | FAM83H antisense RNA 1 (head to head) | FAM85A | FAM85B | FAM86B1 | FAM86B2 | FAM86B2-DT | FAM86B3P | FAM86C1P | FAM86C2P | FAM86DP | FAM86EP | FAM86FP | FAM86HP | FAM86JP | FAM86KP | FAM86MP | FAM87A | FAM87B | FAM88C | FAM88D | FAM88E | FAM88F | FAM89A | FAM89B | FAM8A1 | FAM90A1 | FAM90A10 | FAM90A11P | FAM90A13P | FAM90A14 | FAM90A18 | FAM90A19 | FAM90A20P | FAM90A25P | FAM90A26 | FAM90A27P | FAM90A2P | FAM90A5P | FAM90A6P | FAM90A7 | FAM91A1 | FAM95A | FAM95B1 | FAM95C | FAM98A | FAM98B | FAM98C | FAM99A | FAM99B | FAM9A | FAM9B | FAM9C | FAN1 | FANCA | FANCB | FANCC | FANCD2 | FANCD2OS | FANCE | FANCF | FANCG | FANCI | FANCL | FANCM | Fanconi anemia complex | FANK1 | FAP | FAR1 | FAR2 | FAR2P1 | FAR2P2 | FARP1 | FARP2 | FARS2 | FARS2-AS1 | FARSA | FARSB | FAS | FAS-AS1 | FASLG | FASN | FASTK | FASTKD1 | FASTKD2 | FASTKD3 | FASTKD5 | FAT1 | FAT2 | FAT3 | FAT4 | FATE1 | Fatty Acid Binding Protein | Fatty acid desaturase | FAU | FAUP1 | FAUP4