Understanding NIF3L1: A Protein Involved in Cell Division and Growth

Target Name: NIF3L1

NCBI ID: G60491

Understanding NIF3L1: A Protein Involved in Cell Division and Growth

NIF3L1 (CALS-7) is a protein that is expressed in various tissues throughout the body, including the brain, heart, lungs, and kidneys. It is a key regulator of the cytoskeleton, which is the structure that gives cells their shape and supports their movement.

NIF3L1 is also a potent modifier of the cytoskeleton, allowing it to alter the size and shape of cells. This property makes NIF3L1 an attractive drug target, as researchers are interested in finding ways to target the NIF3L1 protein and regulate its activity.

One way that researchers are investigating NIF3L1 is to use small molecules, such as drugs, to alter its activity. This approach is based on the idea that drugs can interact with specific proteins and cause them to behave differently. Researchers are using a variety of techniques to identify potential small molecules that can interact with NIF3L1 and modify its activity.

Another approach that researchers are using to investigate NIF3L1 is to study its structure and function. This is done through a variety of techniques, including X-ray crystallography, which allows researchers to study the three-dimensional structure of NIF3L1 in great detail.

By studying the structure and function of NIF3L1, researchers have gained new insights into its role in the cytoskeleton and how it functions as a drug target. One of the key findings of these studies is that NIF3L1 is involved in the regulation of cell division and growth.

NIF3L1 is a protein that is expressed in various tissues throughout the body and is involved in the regulation of cell division and growth. As a result, it is an attractive drug target for researchers who are interested in finding ways to target the NIF3L1 protein and regulate its activity. By using a variety of techniques, including small molecules and X-ray crystallography, researchers are working to understand the role of NIF3L1 in the cytoskeleton and how it functions as a drug target.

Protein Name: NGG1 Interacting Factor 3 Like 1

Functions: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation

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