Target Name: NLRP4
NCBI ID: G147945
Other Name(s): PAAD and NACHT-containing protein 2 | CT58 | PYRIN-containing APAF1-like protein 4 | cancer/testis antigen 58 | FLJ32126 | nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4 | RNH2 | CLR19.5 | Ribonuclease inhibitor 2 | Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4 | NALP4_HUMAN | NALP4 | NACHT, leucine rich repeat and PYD containing 4 | PYPAF4 | NACHT, LRR and PYD domains-containing protein 4 | PAN2 | NLR family pyrin domain containing 4 | NACHT, LRR and PYD containing protein 4 | Cancer/testis antigen 58 | ribonuclease inhibitor 2 | PYRIN and NACHT-containing protein 2

NLRP4: Protein Involved in Cellular Signaling and Disease

NLRP4 (Notch-like receptor protein 4) is a protein that plays a crucial role in cellular signaling. It is a member of the NLRP4 family, which is known for their role in the regulation of cellular stress and inflammation. NLRP4 is a protein that is expressed in many different cell types, including neurons, macrophages, and dendritic cells. It is involved in a wide range of cellular processes, including the regulation of inflammation, cell death, and cell survival.

One of the key functions of NLRP4 is its role in the regulation of inflammation. NLRP4 is involved in the formation of a protein complex called the inflammasome, which is a complex that is involved in the regulation of inflammation. The inflammasome is composed of several different proteins, including NLRP4, which is the key regulator of the inflammasome.

In addition to its role in inflammation, NLRP4 is also involved in the regulation of cell death.NLRP4 is involved in the formation of a protein complex called the necroptide-associated protein complex (NACHT), which is composed of several different proteins that are involved in the regulation of cell death. NLRP4 is the leader of the NACHT complex, and it plays a key role in the regulation of cell death by necroptides, which are small proteins that are involved in the regulation of cell death.

Another function of NLRP4 is its role in the regulation of cellular signaling. NLRP4 is involved in the formation of several signaling pathways that are involved in the regulation of cellular signaling. For example, NLRP4 is involved in the regulation of the JAK/STAT signaling pathway, which is involved in the regulation of cellular signaling. NLRP4 is also involved in the regulation of the NF-kappa-B signaling pathway, which is involved in the regulation of inflammation and cellular signaling.

Due to its involvement in a wide range of cellular processes, NLRP4 is a drug target that is being targeted by researchers. Researchers are interested in developing drugs that can inhibit the activity of NLRP4 and its downstream targets in order to treat a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

In addition to its potential as a drug target, NLRP4 is also a potential biomarker. NLRP4 is a protein that is expressed in many different cell types, including neurons, macrophages, and dendritic cells. As such, it is a potential biomarker for a wide range of diseases. Researchers are interested in using NLRP4 as a biomarker for diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Overall, NLRP4 is a protein that plays a crucial role in cellular signaling. It is involved in the regulation of inflammation, cell death, and cellular signaling, and it is a potential drug target and biomarker. Further research is needed to fully understand the role of NLRP4 in cellular signaling and its potential as a drug target and biomarker.

Protein Name: NLR Family Pyrin Domain Containing 4

Functions: May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways

More Common Targets

NLRP5 | NLRP6 | NLRP7 | NLRP8 | NLRP9 | NLRP9P1 | NLRX1 | NMB | NMBR | NMD3 | NMDA receptor | NME1 | NME1-NME2 | NME2 | NME2P1 | NME3 | NME4 | NME5 | NME6 | NME7 | NME8 | NME9 | NMI | NMNAT1 | NMNAT2 | NMNAT3 | NMRAL1 | NMRAL2P | NMRK1 | NMRK2 | NMS | NMT1 | NMT2 | NMTRQ-TTG10-1 | NMTRQ-TTG12-1 | NMTRV-TAC1-1 | NMU | NMUR1 | NMUR2 | NNAT | NNMT | NNT | NNT-AS1 | NOA1 | NOB1 | NOBOX | NOC2L | NOC2LP2 | NOC3L | NOC4L | NOCT | NOD1 | NOD2 | NODAL | NOG | NOL10 | NOL11 | NOL12 | NOL3 | NOL4 | NOL4L | NOL4L-DT | NOL6 | NOL7 | NOL8 | NOL9 | NOLC1 | NOM1 | NOMO1 | NOMO2 | NOMO3 | Non-protein coding RNA 185 | NONO | NOP10 | NOP14 | NOP14-AS1 | NOP16 | NOP2 | NOP53 | NOP56 | Nop56p-associated pre-rRNA complex | NOP58 | NOP9 | NOPCHAP1 | NORAD | NOS1 | NOS1AP | NOS2 | NOS2P1 | NOS2P2 | NOS2P3 | NOS3 | NOSIP | NOSTRIN | Notch ligands | Notch receptor | Notch Transcriptional Activation Complex | NOTCH1 | NOTCH2 | NOTCH2NLA