NKAIN4: A Protein Involved in Brain Function and Neurodegenerative Diseases

Target Name: NKAIN4

NCBI ID: G128414

NKAIN4: A Protein Involved in Brain Function and Neurodegenerative Diseases

NKAIN4 (FAM77A) is a protein that is expressed in various tissues of the body, including the brain. It is a member of the family of N-cadherinrelated proteins, which are known for their role in cell-cell adhesion and tissue organization. NKAIN4 has been shown to be involved in a number of physiological processes in the brain, including the development and maintenance of neural circuits.

One of the unique features of NKAIN4 is its ability to form aggregates in the brain. These aggregates, known as N-cadherin domains, are thought to play a role in the regulation of NKAIN4 function and may be involved in its neurotoxicity. The N-cadherin domains are composed of a series of amino acids that are highly conserved across different species and are involved in the formation of a transmembrane region that is thought to be involved in the formation of aggregates.

NKAIN4 has also been shown to be involved in the regulation of neurotransmitter release from neurons. In addition, it has been shown to play a role in the development and maintenance of synapses, which are the structural and functional connections between neurons.

In addition to its role in neurotransmission and synaptic development, NKAIN4 is also thought to be involved in the regulation of inflammation. Studies have shown that NKAIN4 is involved in the regulation of the production of pro-inflammatory cytokines, which can contribute to the development of neuroinflammatory diseases.

Given its involvement in a number of important physiological processes, NKAIN4 is a promising drug target. Studies have shown that NKAIN4 is involved in a number of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In addition, NKAIN4 has also been shown to be involved in the development of neuropsychiatric diseases, such as depression and anxiety.

In addition to its potential as a drug target, NKAIN4 is also a potential biomarker for a number of neurodegenerative diseases. The N-cadherin domains of NKAIN4 are thought to be involved in the regulation of cell-cell adhesion, which can be affected in a number of neurodegenerative diseases. Additionally, the regulation of NKAIN4 function by its N-cadherin domains may be involved in the development of neurotoxicity, as has been seen in the regulation of other proteins involved in neurotoxicity.

Overall, NKAIN4 is a protein that is involved in a number of important physiological processes in the brain. Its unique ability to form aggregates in the brain and its involvement in the regulation of neurotransmission, neurotransplantation, inflammation, and neurodegenerative diseases make it a promising drug target and a potential biomarker for a number of neurodegenerative diseases. Further research is needed to fully understand the role of NKAIN4 in these processes and to develop effective treatments for neurodegenerative diseases.

Protein Name: Sodium/potassium Transporting ATPase Interacting 4

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