RRM2: A Potential Drug Target for Cellular Processes (G6241)

Target Name: RRM2

NCBI ID: G6241

RRM2: A Potential Drug Target for Cellular Processes

Ribonucleotide (RNA) redirectase M2 (RRM2) is a protein that plays a crucial role in the process of DNA replication in eukaryotic cells. It is a key enzyme in the DNA replication machinery, responsible for removing a template RNA molecule and creating a new double -stranded RNA molecule. RRM2 is a 23-kDa protein that contains 106 amino acid residues. It is expressed in most eukaryotic cells and is involved in the regulation of DNA replication.

RRM2 is a protein that has been identified as a potential drug target in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Its involvement in these diseases has led to the development of new therapeutic strategies, such as inhibiting RRM2 activity to treat cancer cells.

RRM2 is a protein that can interact with various cellular components, including DNA, RNA, and proteins. Its role in DNA replication is highly regulated by various factors, including the concentration of available nucleotides, the level of error repair, and the activity of other enzymes involved in the replication process.

RRM2 has been shown to play a role in the regulation of cell cycle progression, cell growth, and apoptosis. It is involved in the G1 phase of the cell cycle, which is responsible for cell growth and preparation for cell division. During the S phase , RRM2 helps to ensure that the double-stranded DNA template is properly replicated and that any errors in replication are repaired.

RRM2 is also involved in the regulation of apoptosis, which is a process that is tightly controlled in eukaryotic cells. Apoptosis is a natural response of cells to various stimuli, including exposure to DNA damage or infection. RRM2 is involved in the regulation of apoptosis by ensuring that the DNA template is properly replicated and that any errors in replication are repaired before cell death occurs.

RRM2 has also been shown to play a role in the regulation of inflammation and immune responses. It is involved in the regulation of T cell responses, which are critical for immune defense against infection and disease.

In conclusion, RRM2 is a protein that is involved in various cellular processes that are critical for cell survival and growth. Its involvement in DNA replication, cell cycle progression, apoptosis, and inflammation make it a potential drug target in various diseases. The development of new therapeutic strategies, such as inhibiting RRM2 activity, could lead to the development of new treatments for a variety of diseases.

(1)RRM2: a potential drug target for cancer and neurodegenerative diseases.

(2)Inhibition of RRM2 activity could lead to the development of new therapeutic strategies for cancer and neurodegenerative diseases.

(3)RRM2 is involved in the regulation of DNA replication, cell cycle progression, apoptosis, and inflammation.

(4)RRM2 plays a critical role in the regulation of double-stranded DNA template during DNA replication.

(5)RRM2 is involved in the regulation of apoptosis by ensuring that the DNA template is properly replicated and that any errors in replication are repaired before cell death occurs.

(6)RRM2 is involved in the regulation of T cell responses, which are critical for immune defense against infection and disease.

Protein Name: Ribonucleotide Reductase Regulatory Subunit M2

Functions: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling

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