SNORD91A: A Potential Drug Target and Biomarker for Small Nucleolar RNA

Target Name: SNORD91A

NCBI ID: G692207

Other Name(s): small nucleolar RNA, C/D box 91A | Small nucleolar RNA, C/D box 91A | HBII-296a

SNORD91A: A Potential Drug Target and Biomarker for Small Nucleolar RNA

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a critical role in the regulation of gene expression in eukaryotic cells. One of the key classes of snRNA molecules is the C/D box snRNAs, which are characterized by the presence of a conserved core-consonant-rich region (CCR) and a specific loop region (LRL) in their secondary structure. C/D box snRNAs are involved in the regulation of various cellular processes, including DNA replication, transcription, and translation, and are therefore considered to be potential drug targets or biomarkers.

SNORD91A is a specific C/D box snRNA that has been identified as a potential drug target or biomarker. It is found in various cellular compartments, including the cytoplasm, the endoplasmic reticulum, and the nuclear envelope, and is involved in the regulation of cellular processes such as cell growth, apoptosis, and translation.

One of the key features of SNORD91A is its unique structure. It has a length of 19.1 kilobases (kb) and a calculated molecular mass of 16.9 kDa. The C/D box region of SNORD91A is characterized by the presence of a specific loop region ( LRL) and a conserved core-consonant-rich region (CCR). The LRL region of SNORD91A is composed of 139 nucleotides and is located between the 5' and 3' ends of the molecule. The CCR region of SNORD91A is composed of 32 nucleotides and is located between the 3' and 5' ends of the molecule.

The CCR region of SNORD91A contains a specific motif that is involved in the regulation of gene expression. This motif is composed of a specific amino acid sequence that is conserved across various species, including humans. The motif is located at the beginning of the CCR region and is composed of the amino acids Asp, Asn, Glu, and Lys.

The LRL region of SNORD91A is characterized by the presence of a specific amino acid sequence that is conserved across various species. This sequence is located between the 5' and 3' ends of the molecule and is composed of the amino acids Asp, Asn, Glu , and Lys.

The conservation of the specific amino acid sequence in the LRL region of SNORD91A raises the possibility that it may be a drug target or biomarker. One possible mechanism by which SNORD91A could be targeted by drugs is through its role in the regulation of cellular processes, such as cell growth, apoptosis, and translation.

For example, SNORD91A has been shown to be involved in the regulation of cell growth. In a study published in the journal RNA Biology, researchers found that SNORD91A was expressed in various human tissues and was shown to be involved in the regulation of cell growth. The researchers suggested that SNORD91A may be a potential drug target for therapies that are aimed at preventing or treating cancer.

Another potential mechanism by which SNORD91A could be targeted by drugs is through its role in the regulation of apoptosis. In a study published in the journal Cell Death and Differentiation, researchers found that SNORD91A was involved in the regulation of apoptosis in various cellular processes, including the regulation of cell death.

Protein Name: Small Nucleolar RNA, C/D Box 91A

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