Target Name: SNX20
NCBI ID: G124460
Other Name(s): Selectin ligand-interactor cytoplasmic 1 | Sorting nexin-20 | Sorting nexin-20 (isoform 1) | SLIC-1 | sorting nexin 20 | Sorting nexin 20, transcript variant 1 | selectin ligand-interactor cytoplasmic 1 | selectin ligand interactor cytoplasmic-1 | SLIC1 | Sorting nexin-20 (isoform 2) | selectin ligand interactor cytoplasmic 1 | SNX12 | Sorting nexin 20, transcript variant 2 | SNX20 variant 2 | SNX20_HUMAN | SNX20 variant 1

SNX20: A Protein Implicated in Cell Adhesion, Migration and Cell Survival

SNX20 is a protein that is expressed in various tissues and cell types in the human body. Its function is not well understood, but it is known to be involved in the regulation of cellular processes such as cell adhesion, migration, and invasion. SNX20 has also been shown to interact with several ligands, including selectins, which are a family of transmembrane proteins that play a role in cell-cell adhesion.

The selectin ligand-interactor cytoplasmic 1 (Snx20) gene is located on chromosome X and encodes a protein that contains several predicted transmembrane domains and a cytoplasmic tail. The cytoplasmic tail of the protein is important for its ability to interact with other cellular components, including selectins.

Selectins are a family of transmembrane proteins that are involved in cell-cell adhesion and migration. They are characterized by the presence of an extracellular domain that is involved in these processes, as well as a transmembrane domain that is responsible for the stability of the protein in the cell membrane. The selectin ligand-interactor cytoplasmic 1 (Snx20) gene is responsible for producing the protein that is involved in these processes.

SNX20 has been shown to interact with several different selectins, including E-cadherin, N-cadherin, and vimentin. These interactions are important for the regulation of cellular processes such as cell adhesion, migration, and invasion. SNX20 has also been shown to play a role in the regulation of the cytoskeleton, which is responsible for the structure and movement of cells.

In addition to its role in cell-cell adhesion and migration, SNX20 has also been shown to play a role in the regulation of cell survival. Studies have shown that SNX20 can interact with several stress-responsive pathways, including the p53 pathway. This suggests that SNX20 may be involved in the regulation of cellular stress responses, which are important for the survival of cells under a variety of conditions.

SNX20 has also been shown to play a role in the regulation of cellular signaling pathways. Studies have shown that SNX20 can interact with several different signaling pathways, including the TGF-β pathway and the NF-kappa-B pathway. These interactions are important for the regulation of cellular processes such as cell growth, differentiation, and inflammation.

In conclusion, SNX20 is a protein that is involved in several cellular processes, including cell adhesion, migration, and invasion. Its function is not well understood, but it is known to play a role in the regulation of these processes. The selectin ligand-interactor cytoplasmic 1 (Snx20) gene is located on chromosome X and encodes a protein that contains several predicted transmembrane domains and a cytoplasmic tail. Further research is needed to fully understand the function of SNX20 and its role in cellular processes.

Protein Name: Sorting Nexin 20

Functions: May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion

More Common Targets

SNX21 | SNX22 | SNX24 | SNX25 | SNX27 | SNX29 | SNX29P1 | SNX29P2 | SNX3 | SNX30 | SNX31 | SNX32 | SNX33 | SNX4 | SNX5 | SNX6 | SNX7 | SNX8 | SNX9 | SOAT1 | SOAT2 | SOBP | SOCAR | SOCS1 | SOCS2 | SOCS2-AS1 | SOCS3 | SOCS3-DT | SOCS4 | SOCS5 | SOCS5P5 | SOCS6 | SOCS7 | SOD1 | SOD2 | SOD2-OT1 | SOD3 | Sodium channel | Sodium-Glucose Cotransporter (SGLT) | Sodium-potassium-calcium exchanger | SOGA1 | SOGA3 | SOHLH1 | SOHLH2 | Soluble (cytosolic) protein tyrosine phosphatases | Soluble guanylyl cyclase | Solute Carrier Family 12 | Solute carrier family 29 member | Somatostatin receptor | SON | SORBS1 | SORBS2 | SORBS3 | SORCS1 | SORCS2 | SORCS3 | SORCS3-AS1 | SORD | SORD2P | SORL1 | SORT1 | Sorting and assembly machinery complex | Sorting nexin | SOS1 | SOS2 | SOSS complex | SOST | SOSTDC1 | SOWAHA | SOWAHB | SOWAHC | SOWAHD | SOX1 | SOX1-OT | SOX10 | SOX11 | SOX12 | SOX13 | SOX14 | SOX15 | SOX17 | SOX18 | SOX2 | SOX2-OT | SOX21 | SOX21-AS1 | SOX3 | SOX30 | SOX30P1 | SOX4 | SOX5 | SOX5-AS1 | SOX6 | SOX7 | SOX8 | SOX9 | SOX9-AS1 | SP1 | SP100 | SP110