SNX14: A Potential Drug Target and Biomarker (G57231)
SNX14: A Potential Drug Target and Biomarker
SNX14 is a small non-coding RNA (ncRNA) molecule that has been identified as a potential drug target and biomarker. It is a key regulator of the T-cell receptor (TCR), which is a critical protein that plays a crucial role in the immune system. SNX14 is a highly conserved non-coding RNA molecule that is expressed in a variety of tissues and cells, including human T cells, mouse immune cells, and human cancer cells.
The TCR is a transmembrane protein that is composed of a variable region and a constant region. The variable region contains the T-cell receptor alpha chain, which is the protein that interacts with the antigens. The constant region contains several non-coding RNAs, including SNX14, that are involved in regulating the TCR.
SNX14 is a non-coding RNA molecule that is highly conserved in both humans and animals. It is a single exon that is expressed in a variety of tissues and cells, including human T cells, mouse immune cells, and human cancer cells. SNX14 is highly expressed in T cells, which are a critical part of the immune system that play an important role in fighting off infections and cancer.
SNX14 is involved in regulating the TCR, which is a critical protein that plays a crucial role in the immune system. The TCR is a transmembrane protein that is composed of a variable region and a constant region. The variable region contains the T-cell receptor alpha chain, which is the protein that interacts with the antigens. The constant region contains several non-coding RNAs, including SNX14, that are involved in regulating the TCR.
SNX14 is a key regulator of the TCR, and it is involved in the development and regulation of T cells, which are a critical part of the immune system that play an important role in fighting off infections and cancer. SNX14 is highly expressed in T cells, which are a critical part of the immune system that play an important role in fighting off infections and cancer.
In addition to its role in regulating the TCR, SNX14 is also involved in several other processes in the immune system. For example, SNX14 is involved in the regulation of the T-cell receptor alpha chain, which is the protein that interacts with the antigens. It is also involved in the regulation of the B-cell receptor, which is the protein that interacts with the antigens.
SNX14 is a potential drug target because it is involved in the regulation of the TCR, which is a critical protein that plays a crucial role in the immune system. SNX14 is also a potential biomarker because it is highly expressed in T cells, which are a critical part of the immune system that play an important role in fighting off infections and cancer.
In conclusion, SNX14 is a highly conserved non-coding RNA molecule that is involved in the regulation of the TCR, which is a critical protein that plays a crucial role in the immune system. SNX14 is also a potential drug target and biomarker, and further research is needed to fully understand its role in the immune system.
Protein Name: Sorting Nexin 14
Functions: Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking (By similarity). Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes (PubMed:25848753). Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:25848753, PubMed:25148684)
More Common Targets
SNX15 | SNX16 | SNX17 | SNX18 | SNX18P23 | SNX18P24 | SNX18P3 | SNX19 | SNX2 | SNX20 | SNX21 | SNX22 | SNX24 | SNX25 | SNX27 | SNX29 | SNX29P1 | SNX29P2 | SNX3 | SNX30 | SNX31 | SNX32 | SNX33 | SNX4 | SNX5 | SNX6 | SNX7 | SNX8 | SNX9 | SOAT1 | SOAT2 | SOBP | SOCAR | SOCS1 | SOCS2 | SOCS2-AS1 | SOCS3 | SOCS3-DT | SOCS4 | SOCS5 | SOCS5P5 | SOCS6 | SOCS7 | SOD1 | SOD2 | SOD2-OT1 | SOD3 | Sodium channel | Sodium-Glucose Cotransporter (SGLT) | Sodium-potassium-calcium exchanger | SOGA1 | SOGA3 | SOHLH1 | SOHLH2 | Soluble (cytosolic) protein tyrosine phosphatases | Soluble guanylyl cyclase | Solute Carrier Family 12 | Solute carrier family 29 member | Somatostatin receptor | SON | SORBS1 | SORBS2 | SORBS3 | SORCS1 | SORCS2 | SORCS3 | SORCS3-AS1 | SORD | SORD2P | SORL1 | SORT1 | Sorting and assembly machinery complex | Sorting nexin | SOS1 | SOS2 | SOSS complex | SOST | SOSTDC1 | SOWAHA | SOWAHB | SOWAHC | SOWAHD | SOX1 | SOX1-OT | SOX10 | SOX11 | SOX12 | SOX13 | SOX14 | SOX15 | SOX17 | SOX18 | SOX2 | SOX2-OT | SOX21 | SOX21-AS1 | SOX3 | SOX30 | SOX30P1 | SOX4