Target Name: TM7SF2
NCBI ID: G7108
Other Name(s): Delta(14)-sterol reductase TM7SF2 (isoform 1) | Delta(14)-sterol reductase | delta-14-SR | NET47 | Sterol delta14-reductase | sterol C14-reductase | Putative sterol reductase SR-1 | TM7SF2 variant 1 | Transmembrane 7 superfamily member 2 | DHCR14A | Transmembrane 7 superfamily member 2, transcript variant 1 | C14SR | 3-beta-hydroxysterol Delta (14)-reductase | C-14 sterol reductase | Sterol C14-reductase | Delta(14)-sterol reductase TM7SF2 | putative sterol reductase SR-1 | ANG1 | another new gene 1 protein | ERG24_HUMAN | transmembrane 7 superfamily member 2 | Delta-14-SR | Another new gene 1 protein

TM7SF2: A Potential Drug Target and Biomarker for Steroid Reductase Enzymes

Steroid hormones are essential for various physiological processes in the body, including growth and development, inflammation, and maintenance of cellular function. However, when the production of these hormones becomes imbalanced or disrupted, they can lead to various diseases, such as obesity, diabetes, and cancer. The primary targets of these diseases are the enzymes involved in the synthesis and degradation of steroids. One of these enzymes is TM7SF2 (Delta(14)-sterol reductase TM7SF2), an enzyme involved in the steroid 14-beta-hydroxysteroid dehydrogenase (14-beta-HSD) pathway. In this article, we will discuss TM7SF2 as a potential drug target and biomarker for steroid reduc

Protein Name: Transmembrane 7 Superfamily Member 2

Functions: Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis

More Common Targets

TM7SF3 | TM9SF1 | TM9SF2 | TM9SF3 | TM9SF4 | TMA16 | TMA7 | TMBIM1 | TMBIM4 | TMBIM6 | TMC1 | TMC2 | TMC3 | TMC4 | TMC5 | TMC6 | TMC7 | TMC8 | TMCC1 | TMCC1-DT | TMCC2 | TMCC3 | TMCO1 | TMCO1-AS1 | TMCO2 | TMCO3 | TMCO4 | TMCO5A | TMCO5B | TMCO6 | TMED1 | TMED10 | TMED10P1 | TMED11P | TMED2 | TMED3 | TMED4 | TMED5 | TMED6 | TMED7 | TMED7-TICAM2 | TMED8 | TMED9 | TMEFF1 | TMEFF2 | TMEM100 | TMEM101 | TMEM102 | TMEM104 | TMEM105 | TMEM106A | TMEM106B | TMEM106C | TMEM107 | TMEM108 | TMEM109 | TMEM11 | TMEM114 | TMEM115 | TMEM116 | TMEM117 | TMEM119 | TMEM120A | TMEM120B | TMEM121 | TMEM121B | TMEM123 | TMEM125 | TMEM126A | TMEM126B | TMEM127 | TMEM128 | TMEM129 | TMEM130 | TMEM131 | TMEM131L | TMEM132A | TMEM132B | TMEM132C | TMEM132D | TMEM132D-AS1 | TMEM132E | TMEM132E-DT | TMEM133 | TMEM134 | TMEM135 | TMEM138 | TMEM139 | TMEM139-AS1 | TMEM140 | TMEM141 | TMEM143 | TMEM144 | TMEM145 | TMEM147 | TMEM147-AS1 | TMEM14A | TMEM14B | TMEM14C | TMEM14DP