TMEM109: A Protein Involved in Ion Channel Regulation and Cellular Signaling

Target Name: TMEM109

NCBI ID: G79073

TMEM109: A Protein Involved in Ion Channel Regulation and Cellular Signaling

TMEM109 (TM109_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and liver. It is a member of the transmembrane protein family, which means that it spans the cell membrane and extends into the cytoplasm. TMEM109 is involved in a number of cellular processes that are important for maintaining cellular health and function.

One of the key functions of TMEM109 is its role in the regulation of ion channels. These channels are responsible for allowing and preventing the flow of electrical signals through the cell membrane, and they play a crucial role in the transmission of information within the cell. TMEM109 is involved in the regulation of the Na+/K+-ATPase, a protein that is responsible for maintaining the levels of sodium and potassium ions within the cell.

In addition to its role in ion channel regulation, TMEM109 is also involved in the regulation of cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs, and it is an important part of the development and maintenance of these structures . TMEM109 is involved in the regulation of cell adhesion by interacting with the cadherin protein, which is a protein that is involved in adhesion.

Another function of TMEM109 is its role in the regulation of cell signaling pathways. Signaling pathways are the processes by which cells communicate with one another and with their environment, and they are important for the proper functioning of the cell. TMEM109 is involved in the regulation of several signaling pathways, including the TGF-β pathway and the NF-kappa-B pathway.

In addition to its role in cellular signaling, TMEM109 is also involved in the regulation of cellular processes that are important for the structure and function of the cell. For example, TMEM109 is involved in the regulation of the assembly and disassembly of the cell skeleton, the cell The skeleton is an intracellular scaffolding system that is responsible for maintaining cell morphology, mechanical strength and intracellular transportation. TMEM109 plays a key role in the assembly and disassembly process.

TMEM109 is also involved in the regulation of cell migration. Migration is the process by which cells move from their place of origin to their destination, and it is an important part of the development and progression of tissues and organs. TMEM109 is involved in the regulation of cell migration by interacting with the vimentin protein, which is a protein that is involved in cell migration.

In conclusion, TMEM109 (TM109_HUMAN) is a protein that is involved in a number of important cellular processes that are necessary for maintaining cellular health and function. Its role in ion channel regulation, cell adhesion, cell signaling pathways, and cell migration is just one of the many ways in which TMEM109 contributes to cellular function. As a potential drug target or biomarker, TMEM109 is a promising target for researchers who are interested in the regulation of cellular processes and the development of new treatments for a variety of diseases.

Protein Name: Transmembrane Protein 109

Functions: May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (PubMed:23542032). Can form voltage-gated calcium and potassium channels in vitro (By similarity)

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