UROD: A Versatile Protein Involved in Energy Metabolism and More
UROD: A Versatile Protein Involved in Energy Metabolism and More
UROD (Unregulated RecEAT-Oxidase Domain) is a protein that is expressed in various tissues and organs, including the brain, heart, liver, and kidneys. It is a member of the RecEAT gene family, which is known for its role in the regulation of energy metabolism. UROD is characterized by a unique domain that consists of 24 amino acid residues, known as the RecEAT-Oxidase domain.
The RecEAT-Oxidase domain is a conserved region that is present in a variety of organisms, including bacteria, archaea, and eukaryotes. It is involved in the catalytic activity of the enzyme RecEAT, which is a critical regulator of cellular energy metabolism. The RecEAT-Oxidase domain is responsible for the catalytic activity of the enzyme, as well as its stability and substrate specificity.
UROD is a versatile protein that can be modified to serve as a drug target or biomarker. One of the main advantages of UROD is its high degree of flexibility. Its RecEAT-Oxidase domain can be modified to have different catalytic activities, which can be used to target specific molecules in the body. Additionally, UROD can be modified to have different stability and solubility characteristics, which can be used to improve its stability and effectiveness in the body.
UROD has been shown to be involved in a variety of cellular processes, including energy metabolism, metabolism, and stress response. It has been shown to play a role in the regulation of cellular processes that are important for the health and survival of the body, such as the regulation of cell death, the regulation of inflammation, and the regulation of metabolism.
UROD is also a potential biomarker for a variety of diseases. Its recessive allele has been shown to be associated with a number of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Additionally, UROD has been shown to be involved in the regulation of cellular processes that are important for the development and progression of these diseases, which may be potential targets for diagnostic and therapeutic interventions.
UROD is a unique protein that is expressed in various tissues and organs, and its RecEAT-Oxidase domain makes it a promising drug target or biomarker. Further research is needed to fully understand its role in the regulation of cellular processes and its potential as a drug target or biomarker.
Protein Name: Uroporphyrinogen Decarboxylase
Functions: Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352). Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352). In vitro also decarboxylates pentacarboxylate porphyrinogen I (PubMed:12071824)
More Common Targets
UROS | USB1 | USE1 | USF1 | USF2 | USF3 | USH1C | USH1G | USH2A | USHBP1 | USO1 | USP1 | USP1-UAF1 complex | USP10 | USP11 | USP12 | USP12-AS1 | USP12-DT | USP13 | USP14 | USP15 | USP16 | USP17L1 | USP17L10 | USP17L11 | USP17L12 | USP17L13 | USP17L14P | USP17L15 | USP17L17 | USP17L18 | USP17L2 | USP17L20 | USP17L21 | USP17L24 | USP17L25 | USP17L26 | USP17L27 | USP17L29 | USP17L3 | USP17L5 | USP17L6P | USP17L7 | USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5 | USP50 | USP51 | USP53 | USP54 | USP6 | USP6NL | USP6NL intronic transcript 1 (non-protein coding), transcript variant 1 | USP7 | USP8 | USP8P1 | USP9X | USP9Y
