Target Name: LMAN1L
NCBI ID: G79748
Other Name(s): ERGIC53-like protein | ERGL | Lectin mannose-binding 1-like | LMA1L_HUMAN | LMAN1-like protein | ERGIC-53-like protein | Protein ERGIC-53-like | lectin, mannose binding 1 like | Lectin, mannose binding 1 like | ERGIC-53L

Unlocking the Potential of LMAN1L: AERGIC53-Like Protein as a Drug Target or Biomarker

LMAN1L (long non-coding RNA-protein interaction protein 1-like) is a protein that has recently been identified as an attractive drug target and biomarker. It is a 22-kDa protein that is expressed in various tissues and cells, including brain, heart, and muscle. LMAN1L has been shown to play a critical role in regulating gene expression and has been associated with various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

The Protein Structure and Functions

The protein sequence of LMAN1L is highly conserved and is similar to that of ERGIC53, a well-known transmembrane protein that is involved in the formation of tight junctions in epithelial cells. ERGIC53 is a G protein-coupled receptor (GPCR) that is involved in cell signaling and has been implicated in various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

While the functions of LMAN1L and ERGIC53 are not yet fully understood, both proteins are involved in the regulation of gene expression and have been implicated in various physiological processes. LMAN1L has been shown to interact with various transcription factors, including NF-kappa-B, AP-1, and STAT3, and has been shown to play a role in the regulation of gene expression in various tissues and cells. ERGIC53 has been shown to play a critical role in the regulation of tight junction formation in epithelial cells and has been implicated in the development of various diseases, including cancer.

Drug Target Potential

The drug targeting potential of LMAN1L is high due to its unique structure and functions. LMAN1L is a protein that can be modulated by small molecules, making it an attractive target for drug development. Additionally, LMAN1L has been shown to play a critical role in various physiological processes, making it an attractive target for the development of new drugs that can modulate its functions.

One of the promising strategies for targeting LMAN1L is the use of small molecules that can modulate its expression or activity. Several studies have shown that small molecules such as inhibitors of DNA binding, activators of protein kinase C (PKC), and modulators of nuclear factor kappa B (NF-kappa-B) can modulate the expression of LMAN1L. Additionally, several structural studies have shown that LMAN1L can interact with small molecules such as inhibitors of protein tyrosination and inhibitors of phosphorylation, making these small molecules potential candidates for drug development.

Biomarker Potential

The biomarker potential of LMAN1L is also high due to its involvement in various physiological processes. LMAN1L has been shown to play a critical role in the regulation of gene expression and has been associated with various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

One of the promising strategies for using LMAN1L as a biomarker is the use of techniques such as qRT-PCR, Southern blotting, and Western blotting to measure the expression of LMAN1L in various tissues and cells. These techniques can be used to assess the levels of LMAN1L and to determine its expression patterns in different conditions, such as when LMAN1L is expressed or when it is not. Additionally, the use of antibodies that recognize specific regions of LMAN1L can be used to measure the levels of LMAN1L in various tissues and cells and to determine its expression patterns in different conditions.

Conclusion

In conclusion, LMAN1L is a protein that has the potential to be a drug target or biomarker. Its unique structure and functions, as well as its involvement in various physiological processes, make it an attractive target for drug development and biomarker research. While more research is needed to fully understand the functions of LMAN1L, its potential as a drug target or biomarker is significant.

Protein Name: Lectin, Mannose Binding 1 Like

More Common Targets

LMAN2 | LMAN2L | LMBR1 | LMBR1L | LMBRD1 | LMBRD2 | LMCD1 | LMCD1-AS1 | LMF1 | LMF2 | LMLN | LMNA | LMNB1 | LMNB2 | LMNTD1 | LMNTD2 | LMNTD2-AS1 | LMO1 | LMO2 | LMO3 | LMO4 | LMO7 | LMO7-AS1 | LMO7DN | LMOD1 | LMOD2 | LMOD3 | LMTK2 | LMTK3 | LMX1A | LMX1B | LMX1B-DT | LNC-LBCS | LNCAROD | LNCARSR | LNCATV | LNCNEF | LNCOC1 | LNCOG | LNCPRESS1 | LNCRI | LNCRNA-ATB | LNCRNA-IUR | LNCTAM34A | LNP1 | LNPEP | LNPK | LNX1 | LNX1-AS1 | LNX2 | LOC100127946 | LOC100127955 | LOC100128002 | LOC100128028 | LOC100128050 | LOC100128059 | LOC100128079 | LOC100128093 | LOC100128164 | LOC100128242 | LOC100128288 | LOC100128317 | LOC100128361 | LOC100128398 | LOC100128494 | LOC100128593 | LOC100128770 | LOC100128966 | LOC100128988 | LOC100129034 | LOC100129098 | LOC100129148 | LOC100129175 | LOC100129203 | LOC100129215 | LOC100129316 | LOC100129381 | LOC100129434 | LOC100129455 | LOC100129534 | LOC100129603 | LOC100129697 | LOC100130000 | LOC100130207 | LOC100130285 | LOC100130298 | LOC100130331 | LOC100130452 | LOC100130463 | LOC100130548 | LOC100130587 | LOC100130691 | LOC100130698 | LOC100130744 | LOC100130748 | LOC100130872 | LOC100130899 | LOC100130938 | LOC100130987 | LOC100130992