Target Name: MIEN1
NCBI ID: G84299
Other Name(s): C35 | C35 protein | HBV XAg-transactivated protein 4 | HBV X-transactivated gene 4 protein | C17orf37 | migration and invasion enhancer 1 | MIEN1 variant 1 | Migration and invasion enhancer 1 | Migration and invasion enhancer 1, transcript variant 1 | RDX12 | Migration and invasion enhancer 1 (isoform 1) | ORB3 | Protein C35 | XTP4 | protein C17orf37 | MIEN1_HUMAN | MGC14832

MIEN1: A Potential Drug Target for Melanoma

MIEN1 (Melanoma Invasive Neoplasm 1) is a protein that is expressed in melanoma, which is a type of skin cancer that is highly aggressive and can be deadly. Despite advances in treatment, the survival rate for melanoma remains high, with a five-year survival rate of only 15%.

MIEN1 is a transmembrane protein that is expressed in various tissues, including the skin, hair, and brain. It is involved in cell signaling and is thought to play a role in the development and progression of melanoma.

Recent studies have suggested that MIEN1 may be a drug target for cancer treatments. One study published in the journal Oncology found that inhibiting the activity of MIEN1 reduced the growth of melanoma cells in cell cultures. Another study published in the journal Cancer Research found that adding a small molecule inhibitor to the treatment of melanoma resulted in a significant reduction in the size of tumors.

While these studies are promising, more research is needed to fully understand the role of MIEN1 in melanoma development and treatment.MIEN1 has been identified as a potential drug target by researchers at the University of California, San Diego, who have shown that blocking the activity of MIEN1 using small molecules can result in a significant reduction in the size of melanoma tumors.

In addition to its potential as a drug target, MIEN1 has also been identified as a biomarker for melanoma. A study published in the journal Skin Disease found that MIEN1 was significantly elevated in the skin biopsies of patients with melanoma, and that the levels of MIEN1 were associated with the severity of the disease.

MIEN1 has also been shown to be involved in the development and progression of various other types of cancer, including breast, ovarian, and prostate cancer. This suggests that it may be a useful target for cancer treatments that are effective against multiple types of cancer.

Despite the potential for MIEN1 as a drug target and biomarker, further research is needed to fully understand its role in melanoma development and treatment. Researchers are currently studying the use of small molecules and other therapeutic approaches to block the activity of MIEN1 in melanoma treatment.

In conclusion, MIEN1 is a protein that is expressed in various tissues and is involved in cell signaling. Recent studies have suggested that it may be a drug target for cancer treatments and a biomarker for melanoma. Further research is needed to fully understand its role in melanoma development and treatment.

Protein Name: Migration And Invasion Enhancer 1

Functions: Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process

More Common Targets

MIER1 | MIER2 | MIER3 | MIF | MIF-AS1 | MIF4GD | MIGA1 | MIGA2 | MIIP | MILIP | MILR1 | MIMT1 | MINAR1 | MINAR2 | MINCR | MINDY1 | MINDY2 | MINDY2-DT | MINDY3 | MINDY4 | Minichromosome maintenance (MCM) 2-7 helicase complex | MINK1 | MINPP1 | MIOS | MIOX | MIP | MIPEP | MIPEPP3 | MIPOL1 | MIR1-1 | MIR1-1HG | MIR1-2 | MIR100 | MIR100HG | MIR101-1 | MIR101-2 | MIR10394 | MIR10396B | MIR10399 | MIR103A1 | MIR103A2 | MIR103B1 | MIR103B2 | MIR105-1 | MIR105-2 | MIR10527 | MIR106A | MIR106B | MIR107 | MIR10A | MIR10B | MIR11181 | MIR11400 | MIR11401 | MIR1178 | MIR1179 | MIR1180 | MIR1181 | MIR1182 | MIR1183 | MIR1184-1 | MIR1184-2 | MIR1184-3 | MIR1185-1 | MIR1185-2 | MIR1193 | MIR1197 | MIR1199 | MIR1200 | MIR1202 | MIR1203 | MIR1204 | MIR1205 | MIR1206 | MIR1207 | MIR1208 | MIR12129 | MIR12135 | MIR12136 | MIR122 | MIR1224 | MIR1225 | MIR1226 | MIR1227 | MIR1228 | MIR1229 | MIR1231 | MIR1233-1 | MIR1233-2 | MIR1234 | MIR1236 | MIR1237 | MIR1238 | MIR124-1 | MIR124-1HG | MIR124-2 | MIR124-2HG | MIR124-3 | MIR1243 | MIR1244-1