OLFM4: A Potential Drug Target and Biomarker (G10562)
OLFM4: A Potential Drug Target and Biomarker
OLFM4 (hOLF) is a protein that is expressed in various tissues throughout the body, including the brain. It is a key regulator of cell survival and proliferation, and is involved in many important cellular processes. In recent years, researchers have been interested in studying OLFM4 as a potential drug target or biomarker because of its involvement in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
One of the key features of OLFM4 is its role in cell survival and proliferation. OLFM4 is a transcription factor that regulates the expression of genes involved in cell growth, differentiation, and survival. It has been shown to play a key role in the regulation of neural stem cell proliferation and the development of neural networks. In addition, OLFM4 has also been shown to play a role in the regulation of cancer cell survival and the development of cancer.
Another important function of OLFM4 is its role in the regulation of cellular processes that are important for overall cellular health and function. OLFM4 is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. It is also involved in the regulation of cell migration, which is the process by which cells move from one location to another in the body. In addition, OLFM4 is involved in the regulation of cell apoptosis, which is the process by which cells die when they are no longer needed.
OLFM4 is also involved in the regulation of cellular signaling pathways that are important for many different cellular processes. It is a key regulator of the PI3K/Akt signaling pathway, which is involved in the regulation of cellular signaling pathways that are important for many different cellular processes, including cell survival and proliferation. In addition, OLFM4 is also involved in the regulation of the NF-kappa signaling pathway, which is involved in the regulation of cell growth and differentiation.
In addition to its role in cell survival and proliferation, OLFM4 is also involved in the regulation of cellular processes that are important for overall cellular health and function. It is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. It is also involved in the regulation of cell migration, which is the process by which cells move from one location to another in the body. In addition, OLFM4 is involved in the regulation of cell apoptosis, which is the process by which cells die when they are no longer needed.
As a potential drug target, OLFM4 has been studied for its ability to modulate cellular processes that are involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that OLFM4 can be activated in response to various stimuli, including chemotherapy drugs and neurodegenerative toxins. This suggests that OLFM4 may be a useful target for the development of therapies that can treat these diseases.
In addition to its potential as a drug target, OLFM4 has also been shown to be a potential biomarker for the diagnosis and prognosis of various diseases. For example, studies have shown that OLFM4 levels are elevated in the brains of individuals with neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. This suggests that OLFM4 may be a useful biomarker for the diagnosis and prognosis of these diseases.
Overall, OLFM4 is a protein that is involved in a wide range of cellular processes that are important for the survival and function of cells. As a potential drug target and biomarker, OLFM4 has the potential to be a valuable tool for the development of new therapies for a wide range of diseases. Further research is needed to fully understand the role of OLFM4 in
Protein Name: Olfactomedin 4
Functions: May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin
More Common Targets
OLFML1 | OLFML2A | OLFML2B | OLFML3 | OLIG1 | OLIG2 | OLIG3 | Oligosaccharyltransferase complex | OLMALINC | OLR1 | OMA1 | OMD | OMG | OMP | Oncostatin-M Receptor | ONECUT1 | ONECUT2 | ONECUT3 | OOEP | OOSP1 | OOSP2 | OPA1 | OPA1-AS1 | OPA3 | OPALIN | OPCML | OPHN1 | Opioid receptor | OPLAH | OPN1LW | OPN1MW | OPN1MW3 | OPN1SW | OPN3 | OPN4 | OPN5 | OPRD1 | OPRK1 | OPRL1 | OPRM1 | OPRPN | OPTC | OPTN | OR10A2 | OR10A3 | OR10A4 | OR10A5 | OR10A6 | OR10A7 | OR10AA1P | OR10AB1P | OR10AC1 | OR10AD1 | OR10AF1P | OR10AG1 | OR10AK1P | OR10C1 | OR10D1P | OR10D3 | OR10D4P | OR10G2 | OR10G3 | OR10G4 | OR10G7 | OR10G8 | OR10G9 | OR10H1 | OR10H2 | OR10H3 | OR10H4 | OR10H5 | OR10J1 | OR10J2P | OR10J3 | OR10J5 | OR10K1 | OR10K2 | OR10P1 | OR10Q1 | OR10R2 | OR10S1 | OR10T2 | OR10V1 | OR10W1 | OR10X1 | OR10Z1 | OR11A1 | OR11G2 | OR11H1 | OR11H12 | OR11H13P | OR11H2 | OR11H5P | OR11H6 | OR11H7 | OR11J2P | OR11J5P | OR11K2P | OR11L1 | OR11M1P