Target Name: OR10K1
NCBI ID: G391109
Other Name(s): olfactory receptor OR1-6 | O10K1_HUMAN | Olfactory receptor family 10 subfamily K member 1 | Olfactory receptor 10K1 | OR1-6 | olfactory receptor family 10 subfamily K member 1 | Olfactory receptor OR1-6

OR10K1: A drug target and biomarker for the treatment of neurodegenerative diseases

Neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's diseases are some of the most common causes of dementia and debility in the human population. These conditions are characterized by the progressive loss of brain cells and their inability to function properly, leading to a range of symptoms such as memory loss, cognitive impairment, and mood changes.

Despite the availability of treatments for these conditions, the management of neurodegenerative diseases remains a significant challenge. The lack of effective therapies has led to a significant increase in the number of people with these conditions, and the continued prevalence of these diseases underscores the need for new treatments.

OR10K1: A promising drug target and biomarker

OR10K1, a small molecule that binds to the olfactory receptor OR1-6, has the potential to be a drug target and biomarker for the treatment of neurodegenerative diseases. The olfactory receptor is a transmembrane protein that plays a crucial role in the sense of smell. It is composed of two subunits, OR1 and OR6, which are located on the surface of neurons and sense organs.

OR10K1 has been shown to modulate the activity of the olfactory receptor, leading to changes in neural activity that can be detected using techniques such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). These changes in neural activity may be associated with the progression of neurodegenerative diseases.

OR10K1 may also be used as a biomarker for the diagnosis and monitoring of neurodegenerative diseases. The olfactory system is highly sensitive to changes in the environment, such as changes in temperature, humidity, and air quality, and alterations in the olfactory system have been associated with a range of neurological and psychiatric conditions. By using OR10K1 as a biomarker, researchers may be able to monitor the progression of neurodegenerative diseases and determine the effectiveness of potential treatments.

OR10K1's potential as a drug target and biomarker is further supported by its structure and function. OR10K1 is a small molecule that can be easily synthesized and has a low toxicity. Its small size and low cost also make it an attractive candidate for clinical development.

OR10K1 has been shown to interact with a variety of molecules, including proteins involved in neurotransmitter signaling, ion channels, and intracellular signaling pathways. These interactions may be involved in the regulation of neural activity and the progression of neurodegenerative diseases.

OR10K1 may also be involved in the regulation of the immune system, which is a critical factor in the development and progression of neurodegenerative diseases. Studies have shown that changes in the immune system have been associated with the development of neurodegenerative diseases, and that inhibition of immune responses may be a potential strategy for the treatment of these conditions.

OR10K1's potential as a drug target and biomarker is also an exciting development for the field of neurodegenerative diseases. The continued development of new treatments for these conditions will be critical to the care and treatment of people with these debilitating diseases.

Protein Name: Olfactory Receptor Family 10 Subfamily K Member 1

Functions: Odorant receptor

More Common Targets

OR10K2 | OR10P1 | OR10Q1 | OR10R2 | OR10S1 | OR10T2 | OR10V1 | OR10W1 | OR10X1 | OR10Z1 | OR11A1 | OR11G2 | OR11H1 | OR11H12 | OR11H13P | OR11H2 | OR11H5P | OR11H6 | OR11H7 | OR11J2P | OR11J5P | OR11K2P | OR11L1 | OR11M1P | OR12D2 | OR12D3 | OR13A1 | OR13C2 | OR13C3 | OR13C4 | OR13C5 | OR13C8 | OR13C9 | OR13D1 | OR13F1 | OR13G1 | OR13H1 | OR13J1 | OR13Z2P | OR14A16 | OR14A2 | OR14C36 | OR14I1 | OR14J1 | OR14L1P | OR1A1 | OR1A2 | OR1B1 | OR1C1 | OR1D2 | OR1D4 | OR1D5 | OR1E1 | OR1E2 | OR1E3 | OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1 | OR1N2 | OR1P1 | OR1Q1 | OR1S1 | OR1S2 | OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1