Target Name: OR1G1
NCBI ID: G8390
Other Name(s): OR1G1_HUMAN | olfactory receptor 1G2 | Olfactory receptor 1G1 | Olfactory receptor OR17-8 | OR17-130 | olfactory receptor 17-209 | Olfactory receptor 17-209 | Olfactory receptor, family 1, subfamily G, member 2 | Olfactory receptor family 1 subfamily G member 1 | olfactory receptor OR17-8 | OR17-209 | OR1G2 | Olfactory receptor 1G2 | olfactory receptor, family 1, subfamily G, member 2 | olfactory receptor family 1 subfamily G member 1

OR1G1: A Potential Drug Target and Biomarker

OR1G1 (OR1G1_HUMAN), a protein that belongs to the OR1G1 family, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. OR1G1 plays a crucial role in various cellular processes, including cell signaling, DNA replication, and apoptosis. Its functions have been studied extensively, and its potential as a drug target have been evaluated in numerous preclinical and clinical studies.

The OR1G1 gene, which encodes a protein with 181 amino acid residues, is located on chromosome 6p21. It is a member of the OR1G1 family, which includes several similar genes, such as OR1G1, OR1G2, and OR1G3. These genes are involved in various cellular processes, including cell signaling, DNA replication, and apoptosis. OR1G1 has been shown to play a crucial role in regulating cell proliferation, cell survival, and cellular processes that are essential for the development and maintenance of tissues.

OR1G1 functions as a negative regulator of the p53 tumor suppressor gene. p53 is a well-known gene that plays a crucial role in maintaining genomic stability, and it is often mutated in various diseases, including cancer. OR1G1 functions as a negative regulator of p53 by preventing its transcriptional activity. This means that when OR1G1 is expressed in cells, it can inhibit the activity of p53, leading to the activation of p53 target genes that can promote cell growth and survival.

OR1G1 has been shown to play a role in various diseases, including cancer. For example, OR1G1 has been shown to be downregulated in various types of cancer, including breast cancer, lung cancer, and colon cancer. This suggests that OR1G1 may be a potential drug target for these diseases. Additionally, OR1G1 has been shown to be involved in the regulation of cell apoptosis, which is a natural process that is essential for the development and maintenance of tissues. The regulation of cell apoptosis by OR1G1 has been shown to be involved in the development and progression of various diseases, including neurodegenerative diseases and autoimmune disorders.

OR1G1 has also been shown to be involved in the regulation of DNA replication. DNA replication is a critical process that is essential for the development and maintenance of all living organisms. OR1G1 has been shown to play a role in regulating DNA replication by preventing its transcriptional activity. This means that when OR1G1 is expressed in cells, it can inhibit the activity of the enzyme responsible for DNA replication, leading to the accumulation of mutations in the DNA. This accumulation of mutations can lead to the development of various diseases, including cancer.

In conclusion, OR1G1 is a protein that has been extensively studied for its functions in various cellular processes. Its functions have been shown to be involved in the regulation of cell proliferation, cell apoptosis, and DNA replication. OR1G1 has also been shown to play a role in the development and progression of various diseases, including cancer. Based on these findings, OR1G1 is a potential drug target and biomarker for various diseases. Further research is needed to fully understand the functions of OR1G1 and its potential as a drug.

Protein Name: Olfactory Receptor Family 1 Subfamily G Member 1

Functions: Odorant receptor

More Common Targets

OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1 | OR1N2 | OR1P1 | OR1Q1 | OR1S1 | OR1S2 | OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1