Potential Drug Target and Biomarker for Pain Management (G391211)
Potential Drug Target and Biomarker for Pain Management
Olfactory receptor 2G6 (OR2G6) is a protein that is expressed in the vomiting cells of the olfactory system, which is responsible for transmitting sensory information from the nose and mouth to the brain. Mutations in the OR2G6 gene have been linked to a range of disorders, including chronic insomnia, anxiety, and depression. Additionally, altered OR2G6 expression has also been implicated in various cancers, including breast and ovarian cancer.
Recent studies have also shown that OR2G6 is involved in the regulation of pain perception, and that it may play a role in the development of chronic pain conditions. This is because OR2G6 is known to interact with a protein called GPR91, which is a G protein-coupled receptor that is involved in pain signaling. By modulating GPR91 activity, OR2G6 may be able to influence pain sensitivity and contribute to the development of chronic pain.
Another promising aspect of OR2G6 is its potential as a drug target. Many drugs that are currently in use for treating chronic pain conditions work by blocking the activity of GPR91, which is why OR2G6 is a promising target for new pain medications. By targeting OR2G6, researchers may be able to develop drugs that specifically target this protein and reduce the risk of side effects associated with current pain medications.
Additionally, OR2G6 may also be a useful biomarker for monitoring the effectiveness of pain medications. Since OR2G6 is expressed in the vomiting cells of the olfactory system, changes in its expression levels may indicate that a particular pain medication is having the desired effect. This could be a useful tool for evaluating the effectiveness of different pain treatments and could help doctors to make more informed decisions about the use of pain medications.
Overall, OR2G6 is a protein that has the potential to be a drug target and a biomarker for monitoring the effectiveness of pain medications. Further research is needed to fully understand its role in the olfactory system and its potential as a therapeutic target.
Protein Name: Olfactory Receptor Family 2 Subfamily G Member 6
Functions: Odorant receptor
More Common Targets
OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9 | OR4E2 | OR4F13P | OR4F15 | OR4F16 | OR4F17 | OR4F21 | OR4F29 | OR4F3 | OR4F4 | OR4F5 | OR4F6 | OR4G3P | OR4K1 | OR4K13 | OR4K14 | OR4K15 | OR4K17 | OR4K2 | OR4K5 | OR4K6P
