OR2T3: A G Protein-coupled Receptor Involved in Olfactory Function and Neurological Disorders

OR2T3: A G Protein-coupled Receptor Involved in Olfactory Function and Neurological Disorders

OR2T3, a member of the Olfactory Receptor Family 2 (ORF2), is a G protein-coupled receptor that plays a crucial role in mediating olfactory function in the human nose. OR2T3 is expressed in the lateral walls of the olfactory bulbs and is involved in the perception of olfactory information. Its function is closely linked to the development and progression of several neurological disorders, including Alzheimer's disease, Parkinson's disease, and migraine.

The Olfactory Receptor Family 2 (ORF2) is a large gene family that includes over 20 members. ORF2 is one of the subfamilies of ORF2 and is responsible for the development and function of the OR2T3 receptor. OR2T3 is a small transmembrane protein that is expressed in the lateral walls of the olfactory bulbs, which are the parts of the nose responsible for the sense of smell.

OR2T3 is involved in the perception of a wide range of olfactory stimuli, including scents, such as those associated with food, drugs, and environmental stimuli. OR2T3 is also involved in the regulation of olfactory sensitivity and in the modulation of olfactory responses. In addition , OR2T3 is involved in the development and progression of several neurological disorders, including Alzheimer's disease, Parkinson's disease, and migraine.

One of the key functions of OR2T3 is its role in the regulation of olfactory sensitivity. Olfactory sensitivity is the ability of the nose to detect and respond to the olfactory stimulus that are present in the environment. OR2T3 plays a crucial role in the regulation of olfactory sensitivity by controlling the activity of the olfactory neurons that are responsible for transmitting the olfactory information from the olfactory bulbs to the brain.

In addition to its role in olfactory sensitivity, OR2T3 is also involved in the regulation of olfactory responses. Olfactory responses are the changes in the activity of the olfactory neurons that are triggered by the presence of a particular scent. OR2T3 plays a role in the regulation of olfactory responses by controlling the activity of the olfactory neurons that are responsible for transmitting the olfactory information from the olfactory bulbs to the brain.

OR2T3 is also involved in the development and progression of several neurological disorders, including Alzheimer's disease, Parkinson's disease, and migraine. These disorders are characterized by the progressive loss of nerve cells and the damage to the nervous system that results. OR2T3 is thought to be involved in the development and progression of these disorders by playing a role in the regulation of the growth and survival of the nerve cells that are responsible for transmitting the olfactory information from the olfactory bulbs to the brain.

In conclusion, OR2T3 is a key gene that is involved in the development and regulation of olfactory function. Its role in the regulation of olfactory sensitivity and responses, as well as its involvement in the development and progression of neurological disorders, make it an attractive target for drug development. Further research is needed to fully understand the role of OR2T3 in olfactory function and its potential as a drug target.

Protein Name: Olfactory Receptor Family 2 Subfamily T Member 3

Functions: Odorant receptor

More Common Targets

OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9 | OR4E2 | OR4F13P | OR4F15 | OR4F16 | OR4F17 | OR4F21 | OR4F29 | OR4F3 | OR4F4 | OR4F5 | OR4F6 | OR4G3P | OR4K1 | OR4K13 | OR4K14 | OR4K15 | OR4K17 | OR4K2 | OR4K5 | OR4K6P | OR4K7P | OR4L1 | OR4M1 | OR4M2 | OR4M2-OT1 | OR4N2 | OR4N3P | OR4N4 | OR4N5 | OR4P4 | OR4Q3 | OR4S1 | OR4S2 | OR4T1P | OR4V1P | OR4X1 | OR4X2 | OR51A1P | OR51A2 | OR51A3P | OR51A4 | OR51A6P | OR51A7 | OR51B2 | OR51B4 | OR51B5 | OR51B6 | OR51C1P | OR51D1 | OR51E1 | OR51E2