Target Name: OR2K2
NCBI ID: G26248
Other Name(s): HSHTPCRH06 | olfactory receptor family 2 subfamily K member 2 | HTPCRH06 | Olfactory receptor OR9-17 | olfactory receptor, family 2, subfamily AN, member 1 pseudogene | Olfactory receptor, family 2, subfamily AR, member 1 pseudogene | OR2K2_HUMAN | OR2AR1P | OR2AN1P | Olfactory receptor family 2 subfamily K member 2 | Olfactory receptor 2K2 | olfactory receptor OR9-17 | Olfactory receptor, family 2, subfamily AN, member 1 pseudogene | olfactory receptor, family 2, subfamily AR, member 1 pseudogene

Heart Failure Drug Target: HSP2

OR2K2 (HSHTPCRH06) is a highly expressed gene in human heart tissue that is associated with the development and progression of heart failure. The gene encodes for a protein known as heat shock protein 2 (HSP2), which is a well-known protein that is involved in a variety of cellular processes, including stress response, DNA damage repair, and cell signaling.

In recent years, researchers have become increasingly interested in the potential of HSP2 as a drug target or biomarker for the treatment of heart failure. This is because HSP2 has been shown to play a role in the regulation of cellular processes that are important for heart function, such as contractility, inflammation, and fibrosis.

One of the key reasons for the interest in HSP2 as a potential drug target is its ability to interact with a variety of signaling pathways that are involved in heart failure. For example, HSP2 has been shown to play a role in the regulation of the renin-angiotensin-aldosterone system (RAAS), a signaling pathway that is involved in the regulation of blood pressure and fluid balance.

Research has also shown that HSP2 is involved in the regulation of the myocardial fibrosis, a process that is thought to contribute to the development of heart failure. Fibrosis is the excessive accumulation of extracellular matrix (ECM) components in tissues, and it is believed to play a key role in the regulation of tissue repair and regeneration.

In addition to its role in fibrosis, HSP2 has also been shown to be involved in the regulation of cell signaling pathways that are important for heart function. For example, HSP2 has been shown to play a role in the regulation of the contractility of heart muscle, which is important for maintaining normal heart rhythm and pumping blood to the body.

Despite the potential implications of HSP2 as a drug target or biomarker for heart failure, there are currently no FDA-approved drugs that are specifically targeting HSP2. However, researchers are actively working to develop new drugs that can inhibit the activity of HSP2 and prevent or reverse the development of heart failure.

In conclusion, OR2K2 (HSHTPCRH06) is a promising drug target or biomarker for the treatment of heart failure due to its involvement in the regulation of cellular processes that are important for heart function. Further research is needed to develop new drugs that can specifically target HSP2 and prevent or reverse the development of heart failure.

Protein Name: Olfactory Receptor Family 2 Subfamily K Member 2

Functions: Odorant receptor

More Common Targets

OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P | OR2Y1 | OR2Z1 | OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9 | OR4E2 | OR4F13P | OR4F15 | OR4F16 | OR4F17 | OR4F21 | OR4F29 | OR4F3 | OR4F4 | OR4F5 | OR4F6 | OR4G3P | OR4K1 | OR4K13 | OR4K14 | OR4K15 | OR4K17 | OR4K2 | OR4K5 | OR4K6P | OR4K7P | OR4L1 | OR4M1 | OR4M2 | OR4M2-OT1 | OR4N2 | OR4N3P | OR4N4