Olfactory Receptor OR1E3 as A Potential Drug Target and Biomarker

Olfactory Receptor OR1E3 as A Potential Drug Target and Biomarker

Olfactory receptor, family 1, subfamily E, member 3 (OR1E3) is a protein that plays a crucial role in the sense of smell. It is a member of the superfamily of G protein-coupled receptors (GPCRs), which are a family of transmembrane proteins that play a major role in cellular signaling. OR1E3 is a GPCR that is expressed in the sensory neurons of the nose, and it is responsible for mediating the sense of smell.

OR1E3 is a 21-kDa protein that is expressed in the neurons of the lateral and upper nasal cavities. It is a GPCR that is part of the superfamily of GPCRs, which are a family of transmembrane proteins that play a major role in cellular signaling. GPCRs are characterized by the presence of a transmembrane domain, a cytoplasmic domain, and an extracellular loop.

OR1E3 is involved in the sense of smell, which is the ability to perceive and identify different scents. It is sensitive to a wide range of scents, including sweet, sour, and ammonia. OR1E3 is also involved in the detection of changes in the concentration of air in the nose, which is important for maintaining the proper pressure and temperature of the nasal environment.

OR1E3 is a protein that is often targeted by drugs as a potential drug target or biomarker. One of the main reasons for this is the fact that OR1E3 is a well-established drug target for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

OR1E3 has been shown to be involved in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that high levels of OR1E3 are associated with an increased risk of cancer, particularly breast and ovarian cancer. Additionally, OR1E3 has been shown to be involved in several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

In addition to its involvement in disease, OR1E3 is also a potential biomarker for several diseases. For example, studies have shown that OR1E3 levels are elevated in the brains of individuals with Alzheimer's disease, and that these levels are associated with the severity of the disease . Additionally, OR1E3 has been shown to be involved in the regulation of the immune system, which is important for the immune response to diseases.

OR1E3 is a protein that is involved in the sense of smell and has been shown to be involved in several diseases. It is a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of OR1E3 in these diseases and to develop effective treatments.

Protein Name: Olfactory Receptor Family 1 Subfamily E Member 3 (gene/pseudogene)

Functions: Odorant receptor

More Common Targets

OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1 | OR1N2 | OR1P1 | OR1Q1 | OR1S1 | OR1S2 | OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1 | OR2W1-AS1 | OR2W3 | OR2W5P | OR2W6P